Objetivou-se identificar a existência da automedicação por populares com a finalidade de prevenção ao SARS-CoV-2 e analisar os potenciais agravamentos deste uso ao organismo humano. Trata-se de uma pesquisa descritiva e analítica, de natureza quantitativa, onde a coleta de dados desse estudo foi realizada através de um formulário semiestruturado, disponibilizado de forma eletrônica, utilizando a ferramenta Google Forms. Os critérios de inclusão compreendem: usuário de rede social e que responderam o formulário no período estabelecido pelos pesquisadores. Há a prevalência de participantes do sexo feminino e portadores de ensino fundamental e superior completo, no qual não houve predomínio da prática de automedicação. Os maiores índices de automedicação aos fármacos Ivermectina e Azitromicina, a maioria dos indivíduos adquiriram esses medicamentos através da farmácia comercial. Portanto é importante ressaltar que não se deve ingerir fármacos sem a orientação médica, o que demostra a importância de que os profissionais de saúde bem como os veículos midiáticos, conscientizem a população sobre os cuidados que devem ser tomados e os riscos que eles podem sofrer ao se automedicar.
Objective To analyze the scientific production regarding maternal folic acid (FA) supplementation and its relationship with autistic spectrum disorder (ASD). Data Sources We performed unrestricted electronic searches in the BIREME virtual bank, Virtual Health Library (VHL) and Medical Literature Analysis and Retrieval System Online (MEDLINE/PubMed) databases. Selection of Studies For sample selection, articles that met the proposed objectives were included, published in English, Spanish and Portuguese, the use of Health Sciences Descriptors (DeCS): autistic OR autism AND autism spectrum disorder AND folic acid, AND, with the use of the Medical Subject Headings (MeSH): autistic OR autism AND autistic spectrum disorder AND folic acid. Data Collection Data extraction was performed by the reviewers with a preestablished data collection formulary. Data Synthesis The Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) was used based on a checklist with 27 items and a 4-step flowchart. Results A total of 384 articles was found by the search strategies, of which 17 were eligible following the pre-established criteria. The main findings of the present review point to maternal FA supplementation in the pre-conception period and beginning of pregnancy as a protective effect in relation to ASD, which should be indicated in this period as prevention to the problem. Conclusion According to the research analyzed, more studies are necessary to know its effects on pregnancy, since the consumption of excessive FA may not be innocuous.
The aim of this study was to determine the activity of cytokinin dehydrogenase (CKX) and to measure other biochemical components in the primary leaves and radicles of castor seedlings (BRS Energia) in the initial phase of growth. The crude protein extract obtained after a 1-h extraction from the root tissues of seedlings showed nodetectable CKX enzymatic activity when incubated with the substrate isopentenyl adenine for 1 h. However, after precipitation with ammonium sulfate at 70% saturation, the pellet showed CKX activity. The peroxidase enzyme activity was higher in the leaves than in the radicles. The total and reducing sugar content was 1.5 times higher in the leaves than in the radicles. The amino acid and protein contents were 6.4 and 9.2 times higher in the leaves than in the radicles, respectively.
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