In her various roles as First Lady, Senator, Secretary of State, and Democratic presidential nominee, Hillary Clinton has long maintained that the subjugation of women poses a national security threat to the United States. Clinton’s proposition has come to be termed the “Hillary Doctrine.” Yet does this principle receive support from the empirical record? In this paper, we offer a test of the Hillary Doctrine by analyzing if more anti-American terrorism emanates from countries that restrict women’s rights than from countries that are not gender restrictive. Using a time series, cross-national analysis of 156 countries from the period 1981 to 2005, our negative binomial models offer strong support for the Hillary Doctrine and suggest that the promotion of women’s rights may well enhance the national security of the United States with respect to terrorism. These results are robust to a wide range of changes to the empirical research design.