Objectives: Obtaining and maintaining pregnancy after intracytoplasmic sperm injection (ICSI) may be affected by many technical factors. The goal of this study is to determine the rates of success from ICSI technique with established parameters and assess the associated factors to its success to treat infertility. Methods: A cross-sectional study involving 115 infertile couples submitted to ICSI was performed to test the association between technical aspects and success rates, from July 2013 to December 2014. Data collection was done through medical records. The bivariate associations were calculated by prevalence ratios and a Poisson regression was performed with significance level p < 0.05. Results: The aspiration of eight or more oocytes was 0.73 times (CI 95% 0.57-0.94) less associated (p = 0.014), but transferring two or more embryos was 1.75 times (CI 95% 1.54-1.99) more associated with the viable pregnancy (p < 0.001). The remaining characteristics of the ICSI procedures were not significantly associated with the expected outcome. Conclusions: The prevalence of the viable pregnancy after ICSI procedure was 40.9%. This index was positively influenced by the aspiration of less than eight oocytes and the transferring of two or more embryos.