The serum vitamin D₃ levels in patients with neurofibromatosis 1 has been reported to be significantly lower than that in control subjects, and the level of vitamin D₃ reversely correlates with the severity of neurofibroma formation. We found that narrowband ultraviolet B (NB-UVB) irradiation increased the serum level of 1,25(OH)₂ vitamin D₃ in patients with neurofibromatosis 1. The difference in the 1,25(OH)₂ vitamin D₃ levels between patients who had received irradiation for more than 18 months and those who had no irradiation was highly significant. Time-course analyses of the serum vitamin D₃ levels in the patients who were enrolled after informed consent revealed that the levels became higher significantly after 6 months of irradiation. It is suggested that NB-UVB irradiation is effective for increasing the serum level of vitamin D₃ in patients with neurofibromatosis 1, which may be of benefit for skin symptoms such as pigmented macules or neurofibromas.
Volumetric displays with a laser excitation of screen materials make voxels in the real space. The laser drawing method can render volumetric graphics with a wide viewing angle because these is no physical wiring between drawing space and system to generate voxels. In our research, a holographic laser-drawing method based on a computer-generated hologram (CGH) displayed on a liquid-crystal on silicon spatial light modulator (LCOS-SLM) is used to increase the number of voxels per a unit time. In this presentation, we will present recent developments of the volumetric displays with the holographic laser drawing.
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