Background: Acute Coronary Syndrome (ACS) is a term used to describe symptoms caused by Acute Myocardial Infarction (AMI). At present, risk stratification is carried out with the use of a Global Registry of Acute Coronary Events (GRACE) score as a validated predictor for cardiovascular events among ACS patients. Mean platelet volume (MPV) is an accurate marker of platelet size and can be considered that to be added to the GRACE score to increase the predictive value of the occurrence of major cardiovascular events (MACE). This study aims to seek the comparison between GRACE score independently and GRACE score with the addition of MPV values in predicting major cardiovascular events during in-hospital care in ACS patients. Methods: This study was ambispective cohort study of 219 ACS patients from November 2017 to November 2018. GRACE scores and MPV values were calculated and mace was observed during hospital treatment. An analysis was performed to see the role of MPV addition to GRACE scores in predicting MACE. Results: MPV values and GRACE scores were found to be increased in patients with MACE compared with those who did not. Area under curve (AUC) on the ROC curve obtained 0.786 (95% CI: 0.717-0.855, p<0.001) when the GRACE score was calculated independently, and increased to 0.810 (95% CI: 0.620-0.775, p<0.001) with addition MPV which indicates a combination of MPV and GRACE score increases predictive value. Conclusion: The addition of the MPV value to the GRACE score provides a higher predictive value in predicting MACE in ACS patients in hospital care.

Background:Acute heart failure (AHF) is a life-threatening condition that increase the intensive care unit and total length of stay and also the risk of in-hospital mortality. It has been widely known that blood pressure components are some of the prognostic factors of heart failure.Objective:To determine association between two main blood pressure components, systolic blood pressure (SBP) and diastolic blood pressure (DBP), as well as mean arterial pressure (MAP) in the clinical settings.Methods:We reviewed the medical records of 50 patients admitted to intensive care unit (ICU) for all-cause acute heart failure within a year. We use three days for ICU and four days for total length of stay (LOS) as the reference categories.Results:Median age, SBP, DBP, and MAP were 63.5 years, 140 mmHg, 80 mmHg, and 103 mmHg, respectively. A statistically significant association was present between SBP (p < 0.018), DBP (p < 0.006), and MAP (p < 0.007) on admission with in-hospital mortality. There was no association found between SBP, DBP, and MAP with the shorter and longer ICU and total length of stay.Conclusion:Among all-cause AHF patients admitted to the ICU, the SBP, DBP, and MAP on admission was associated with in-hospital mortality, respectively.