AIM:To analyse our experiences in the management of traumatic retroperitoneal hematoma (RPH), highlighting the various challenges faced and to report on the outcome of these patients.METHODS:From May 2014 to May 2017, all patients with traumatic RPH who underwent surgical treatment were retrospectively analysed. The kind of injury, intraoperative findings, sites of hematoma, postoperative morbidity and the overall outcomes were recorded.RESULTS:Ninety-six patients; 53 with blunt trauma and 43 with penetrating injury, were included in this study. The centre-medial hematoma was observed in 24 (25%) patients, lateral hematoma in 46 (47.9%) patients, pelvic hematoma in 19 (19.8%) patients, and multiple zone hematomas in 7 (7.3%) patients. All cases were managed surgically. Exploration of the retroperitoneal space was done in 72 cases. Thirty-three patients died, and the overall death rate was 34.4%.CONCLUSION:Surgical exploration should be done in RPH caused by penetrating injury, but the need for urgent exploration in blunt injury is not so high, and it depends on the anatomical site of hematoma, concomitant organ injury and the hemodynamic status of patients.
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is common, yet no curative treatment identified. Cinnamon is a herbal substance, which has many applications in medicine. AIM: The aim of the study was to study the effect of cinnamon on patients with chronic pelvic pain syndrome. METHODS: Sixty patients with documented CP/CPPS randomized into two groups during 2018 and 2019 in Baghdad. The first group received 60 capsules each contained 1 g of cinnamon. The other group received 60 capsules each contained 1 g of sugar powder (placebo). All the patients instructed to take one capsule twice daily for 1 month. National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) was reported for both groups at baseline and after 1 month of treatment. The primary outcome was a patient perceivable improvement defined as a reduction of the NIH-CPSI by 6 or more points after 1 month, whereas improvement of sub-scores of NIH-CPSI (pain, urinary symptoms, and quality of life) considered as a secondary outcome, and adverse reactions reported. RESULTS: Thirteen patients (43.3%) of the cinnamon group have 6 or more points of reduction in the total NIH-CPSI compared to four patients (13.3%) of the control groups (p = 0.01). The improvement in total NIH-CPSI score was mainly due to improvement in pain sub-score, whereas in urinary symptoms, there was marginal change with no significant change in the quality of life score. The only reported side effect was gastric upset in one patient. CONCLUSION: The study concluded that cinnamon improves NIH-CPSI in patients with CP/CPPS. REGISTRATION: The study was registered on ClinicalTrials.gov with the ID: NCT03946163.
Background: The salivary gland pleomorphic adenoma (PA) is a benign epithelial neoplasm, histologically characterized by a great diversity of morphological aspects. It is the most common neoplasm of salivary gland origin. Objective: Studying the histopathological characteristics of PA with special attention to the various morphological features of the epithelial cells and stromal components of this neoplasm. Methods: Hematoxylin and Eosin (H&E) stained tissue sections of 120 cases of PA were reviewed. The tumors were classified according to their histological subtypes as described by Seifert et al. The epithelial components were analyzed considering the type of cells and the morphological pattern. The stromal components were analyzed according to the presence of myxoid, hyaline, chondroid or calcified tissue. Results: This study revealed that most of the tumors were located in the parotid gland (44%). Myxoid or stroma-rich was the most frequent histological subtype (43%). Plasmacytoid cells were the most commonly seen epithelial component (100%), followed by cuboidal cells in (80%) of the cases. Trabecular pattern was the predominant epithelial morphological pattern (90 %), and the myxoid component was the most frequent stromal component (80%). Conclusion: PA of the salivary glands demonstrates a wide variety of cells, stromal components, and morphological characteristics. Since it is the most frequent salivary gland neoplasm that can resemble other salivary gland tumors, the knowledge about these variations is essential for a correct diagnosis. Keywords: Histopathology, pleomorphic adenoma, salivary gland neoplasms Citation: Sarkis SA, Al-Drobie BF, MajeedGH, Al-Marzooq TJM.Histopathological characteristics of pleomorphic adenoma; a retrospective analysis of 120 cases. Iraqi JMS. 2018; Vol. 16(1): 84-91. doi: 10.22578/IJMS.16.1.12
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