BACKGROUND: Most African societies have no tradition of idealized celibacy or voluntary childlessness. Although the norms on parenthood are changing, adults are customarily expected to marry and bear children. AIM: This study examined the perceived value of children among infertile couples in Kwara South, Nigeria. METHODS: Semi-structured interviews were conducted with seven infertile couples recruited through snowball sampling technique. Data were organized using ATLAS.ti 8 and analyzed by thematic analysis. RESULTS: The study revealed that perceptions of the value of children are embedded in sociocultural norms and are strongly linked to religion, patriarchy, and the need for family/marriage sustainability. Childbearing was perceived as the fulfillment of divine injunction; as such, children were regarded as divine. While women believed children are sources of fulfillment and balanced life, most men saw them as life itself. Boys are collectively thought to ensure lineage security and confer honor and prestige on men. A child is believed to give women a permanent seat in marriage. CONCLUSIONS: These insights on the values of children within the Nigerian cultural context can be inculcated in programs and services targeted at alleviating the effect of infertility on childless couples. Innovative cultural programs that will increase the worth of the girl child are also encouraged.