A three-component reaction of arylamines, dialkyl acetylenedicarboxylates and phenacyl bromide in the presence of triphenylphosphine and triethylamine provides an efficient route for the synthesis of N-substituted 2,5-dihydropyrrole derivatives in good yields.
An efficient and green protocol for the synthesis of pyrazolo[1,2-a][1,2,4]triazole-1,3-diones derivatives by one pot, three component coupling reaction of aromatic aldehyde, malononitrile, and 4-phenylurazole has been developed using ZrO 2 nanoparticles (NPs) as the catalyst. The procedure is formed in high yields, short reaction time and an environmentally friendly specificity.
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