Background: Spirituality has been prevalent since the evolution of mankind started. However, the means of practicing spirituality has changed over time. It is claimed by many that any form of spirituality has a positive profound effect on the individuals in various aspects. This research is based on the role played by spirituality on self efficacy, which is people's beliefs about their capabilities to produce results. Methods: Through method of convenient and purposive sampling, 40 participants both male and female were administered with the General Self Efficacy. They were classified as being spiritual or atheist by self report method. Whereby, atheist declared non belief in higher power, and spiritual participants reported belief in higher power. An exact mode of practicing spirituality was not considered. Groups of spiritual individuals and atheists were considered equally in terms of the number of males and females. They were given the General Self-Efficacy Scale. Results: The result was not significant, which is there is no significant difference between spiritual individuals and atheists in terms of self efficacy. Conclusion: Spiritual individuals and atheists do not differ in self efficacy while many factors may remain that determine this relationship