Introduction: The oral health needs of intellectually disabled are complex and may be related to underlying congenital or developmental anomalies as well as the inability to receive adequate personal and professional care to maintain. This research suggests that people with Intellectually Disability such as Mental retardation, are more likely to have poor oral hygiene, periodontal diseases and high incidence of trauma and possibly more likely to have caries than people without Intellectual disability. Aim: The study aims to assess the oral hygiene status and prevalence of malocclusion among special children in tribal population of Southern India. Materials and Methods: Mouth mirror, periodontal probe, straight explorer were used to examine the children. Results: The obtained data are subjected to chi-square test to compare between demographical variables. Statistical significance was fixed at p-value <0.001. Conclusion: We hereby conclude that the maintenance of oral hygiene is difficult among mentally disabled children due to their improper level of understanding. Therefore it is also essential to enlight or to bring awareness and knowledge among the parents, caregivers, about maintaining the proper oral hygiene status and preventive measures. Keywords: Mental Retardation, Malocclusion, Dental Caries, Periodontal Diseases, Treatment Intervention.