Generally, the fluoride ion in drinking water helps to human by preventing tooth decay. But excess fluoride in Drinking water will lead to Dental, and Skeletal fluorosis. Recent studies proved that excess provide in drinking water will produces different organ failures. So risk assessment study was carried in the study area. Total 10 samples collected from the hand pumps in rural village in Kurnool district, Andhra Pradesh state. The collected samples are analyzed for physical parameters and fluoride. The obtained results are compared with BIS standards. The average fluoride concentration observed 0.68 ppm and it is within the prescribed samples specified by BIS. Risk assessment carried out by using hazard quotient. After the investigation, confirmed that no risk observed for the collected samples. Keywords: Fluoride, Dental fluorosis, Skeletal Fluorosis, Physical parameters, Hazard quotient.