A car muffler is a device to improve car noise emission. Some conventional mufflers use layers of glass fiber as a material to absorb noise. However, filling glass fiber is an environmentally unfriendly work, mainly manually filling with chop strand fiber. This research selected a composite material of glass fiber and foam concrete to replace chop strand fiber to avoid this hazard and maintain the muffler’s good noise reduction performance. A response surface methodology with a two-way factorial experimental design repeated the center point twice is performed. The density of the foamed concrete and the weight of the glass fiber is being considered in order to determine the nearly optimal combination of the values in two factors. The response variable is the loudness sensation in Sone of the noise generated from the muffler. At present, the lowest loudness sensation from the two-way factorial design is 16.6494 Sones, which occurred for a muffler with a formula combination of a density of 0.2 g/cm3 and 40 g of glass fiber. The significance of this paper is the presentation of a new application of foam concrete to the green muffler design. To the best of our knowledge, this unique area has never been tackled in the material application of concrete. We have discovered that foam concrete indeed does an excellent job in terms of noise reduction as compared with that of a market muffler.