We present the case of a male patient 39 years old, with a history of primary sclerosing cholangitis for 9 years, complicated with portal hypertension and liver failure, he is in liver transplant program, followed up by Gastroenterology Service. He was admitted for respiratory failure, and massive left pleural effusion, with of features transudate and moderate ascites was noted aswell, we performes pleural and ascitic fluid drainage with concomitant infusion of intravenous albumin. The patient shows good tolerance and significant decrease in both pleural effusion and ascitic fluid. He was discharged in better condition and with increased doses of drugs for the treatment of ascites.