Analyses were performed to construct and confirm the validity of new conjoint intake and 6-month follow-up scales for the Addiction Severity Index (A. T. McLellan, L. Luborsky, G. E. Woody, & C. P. O'Brien, 1980) applied to a diverse sample of substance dependence patients (N -1,008). A multistage scaling strategy identified 5 psychometrically integral addiction problem scales. Exploratory item and factor analyses, confirmatory oblique item clustering, and variance partitioning verified that the scales comprised relatively little common variance and that each retained a substantial amount of unique and reliable variance. Resulting scales (Psychiatric, Drug, Alcohol, Family, and Legal Problems, respectively) were highly internally consistent and structurally stable overall, at intake and follow-up and across gender, age, ethnicity, and substance abuse categories. Concurrent and predictive validity over 2 years were supported for clinical subsamples based on comorbid psychopathology and mood, HIV risk behaviors, personality indices, urine toxicology, and criminal records.The Addiction Severity Index (ASI) is remarkably useful multidimensional clinical and probably the most commonly used instrument in evaluation tool (Cacciola et al., 1997; Stoffelthe field of substance abuse and has been a mayr, Mavis, & Kasim, 1994). At the same time, research in the past decade has begun to demonstrate some limitations in the two sets of