No abstract

Li2CO3 alone was administered to a 21‐year‐old female, who was in a manic state. As a consequence, lactation occurred on about the 50th day after Li2CO3 administration started, and the volume of lactation changed in parallel with the serum Li2CO3 level. The basal plasma PRL concentration and the responses to TRH (500,μ.g) were elevated during Li2CO3 administration. However, both of them returned to within the normal range after the suspension of Li2CO3 administration. From the above‐mentioned findings, it is suggested that lactation is closely related to the Li2CO3 administration.

Summary Changes in blood ammonia levels induced by intracerebral electrical stimulation were studied in rabbits with permanently implanted electrodes in the hypothalamus and the thalamus. Stimulation of the ventromedial nucleus of the hypothalamus for a period of two hours resulted in blood ammonia levels 1.5 to 2 times as high as those of the non‐stimulated controls, but after a 6‐hour stimulation period these levels returned to equal those of the controls, and after a 12‐hour stimulation period of the same nucleus they tended to become less. Stimulation of the lateral hypothalamic area or the centre médian nucleus of thalamus elicited no significant change in blood ammonia levels. The possibility that ammonia metabolism in the liver may be modified through some functional linkage between the brain and the liver was suggested.

No abstract

No abstract