The problem of the geopolitical stability of the country has always been the basis of sustainable economic development. CIS countries and their closest neighbours are the international centres where important transport and communication routes from Asia to Europe intersect. They have a wide range of various raw material reserves, which focuses the world community's attention and builds a separate vector of economic relations. The transformation processes that have taken place in recent years in countries have been due to scientific and technological progress, the intensity of global innovation, and globalization trends, which encourage the country to move to a new level of development. This article summarizes the arguments and counterarguments within the scientific discussion on the place and prospects of CIS countries' international economic position in the formation of the basis for innovative development. The main purpose of the study is to confirm the hypothesis about the functional links between foreign trade and investment activities of countries and the level of innovative development of the country according to the level of economical development. The study's methodological tools were the methods of correlation-regression analysis and simultaneous structural equations, which allow formalizing both explicit and latent relationships between the studied objects. The study period was chosen from 2011 to 2018 because of statistical data availability. In this regard, the array of input data is presented in the form of regressors which identify the level of innovation development countries and three dependent variables (regressands) which indicate the dynamics of foreign trade turnover, doing business and total internal economic conditions. Besides, the variables from each defined block participate as both dependent and independent variables during the construction of the structural model. The results of the study could be useful for The Innovation Agencies, which are established under the Ministry of Transport, Communications and High Technologies of these countries that assist local business entities in acquiring modern technologies and technological solutions