Introduction: Individuals undergoing onco-hematologic treatment present higher risk for developing oral and/or systemic infections, due to the intense immunosuppression and compromise of the mucosal barriers during treatment. The aim of this study was to identify the fungal and viral oral infections that most frequently affected patients undergoing onco-hematologic treatment in a University Hospital, and relate them to the biopsychosocial data, underlying disease and treatment. Methods: This was a crosssectional study in which descriptive analysis of the data was performed, and the Exact Fisher test was applied to verify the association between the infections and the variables: sex, age group, educational level, underlying disease and treatment, considering a 5% probability of error. Results and Discussion: The clinical exam revealed that oral candidiasis was present in 8.92% of the individuals, and herpes simplex, in 4.5%. No significant associations were found between the variables and infections. The fungal and viral oral infections were little prevalente in individuals with hematologic neoplasms in the present study, suggesting that the action of dental surgeons in caring for the onco-hematologic patients at the Institution evaluated and the protocols use were efficient.
Objetivo: Relatar o caso de um paciente com diagnóstico de Síndromeda Imunodeficiência Adquirida (SIDA) e Sarcoma de Kaposi (SK)tendo como sítio primário a cavidade bucal. Descrição do caso: Pacientedo sexo masculino, previamente hígido, apresentou um quadrode astenia, tosse seca, perda ponderal, esplenomegalia e odinofagia.Paciente foi encaminhado para um Hospital Universitário, onde foi realizadoum teste rápido para Vírus da Imunodeficiência Humana (VIH),sendo positivo para o mesmo. O paciente não sabia sobre a infecçãodo vírus e devido ao quadro de imunossupressão severa com contagemde células CD4 de apenas 5 células/mm³e carga viral de 246.441cópias/mlapresentava infecções secundárias à SIDA.No exame odontológico,foi observadauma lesão em palato duro de coloração arroxeada,compatível com SK, tal lesão apresentouum curso rápido einvasivo, comconsequente disseminação da doença.Para determinaro diagnóstico foi realizada uma biopsia incisonal da lesão sob profilaxiaantibiótica, devido ao quadro de imunossupressão do paciente.O resultado do diagnóstico patológico foi de SK. Com isso, o pacientefoi encaminhado para tratamento especializado. Conclusão: O SK frequentementetem como sítio primário a boca, por isso, é importante oconhecimento do cirurgião-dentista sobre esse tipo de lesão para queseja possível a realização do diagnósticoprecoce, no intuito de realizarmedidas terapêuticas necessárias para atenuar os sintomas e melhorara qualidade de vida do paciente.ABSTRACTPurpose: To report the case of a patient diagnosed with Acquired ImmuneDeficiency Syndrome (AIDS) and Kaposi’s Sarcoma (KS) with thebuccal cavity as the primary site. Case description: A previously healthymale patient had asthenia, dry cough, weight loss, splenomegaly, andodynophagia. Patient was referred to a University Hospital, where arapid test for Human Immunodeficiency Virus (HIV) was performed,being positive for it. The patient did not know about virus infectionand due to severe immunosuppression with a CD4 cell count of only5 cells / mm³ and a viral load of 246,441 copies / ml had infectionssecondary to AIDS. In the dental examination, a lesion was found ona hard palate of purplish coloration, compatible with KS, such lesionpresented a rapid and invasive course, with consequent disseminationof the disease. In order to determine the diagnosis, an incisional biopsy of the lesion under antibiotic prophylaxis was performed, due tothe immunosuppression of the patient. The result of the pathologicaldiagnosis was SK. With this, the patient was referred for specializedtreatment. Conclusion: The KS often has a primary site of mouth, soit is important the knowledge of the dental surgeon about this typeof lesion, so that early diagnosis can be made in order to perform thenecessary therapeutic measures to reduce the symptoms and improvethe patient’s quality of life.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.