Objective: To identify, from the scientific production, nursing actions for children and adolescents during the chemotherapy treatment; Classify nursing actions, identified in the literature, according to the domains of taxonomy NIC (Nursing Interventions); Compose a frame of reference with the main Nursing Interventions, according to Taxonomy NIC, for children and adolescents during the chemotherapy treatment. Method: This is an integrative review that aims to identify nursing interventions for children and adolescents with cancer during chemotherapy. Results: We identified ten nursing actions. These were classified according to the domains of taxonomy NIC (Nursing Interventions). Conclusion: The psychological intervention, professionals support and the presence of the family with the child and/or adolescent generate positive results during treatment and after the end of it. The main focus on this research is to show that the nursing care provided to children and adolescents with cancer should not be limited to the biological body, but also consider them as beings in growth and development