The objective was to evaluate the history of traumatic dental injury (TDI) among children with and without autism spectrum disorders (ASD) at the Centro Integrado de Educação Especial (CIES), in Teresina, Brazil. The dental records of 228 children, 114 with ASD (SG = study group) and 114 without ASD (CG = control group), paired by age, gender and socioeconomic characteristics between January 2007 and September 2014 were reviewed. Data were analyzed using chi-square test and multivariate logistic regression (alpha = 5.0%). Dental trauma in SG was lower than in the CG (24.6% and 41.2%, respectively, p = 0.007). The risk of trauma was lower among males in SG (OR: 0.35; 95%CI: 0.18 to 0.67). The likelihood of TDI in SG was 3.17 higher in females than that of males (p = 0.040). The prevalence of TDI was lower in ASD individuals compared to controls. Dental trauma was higher among ASD girls than ASD boys.

Objective To evaluate the impact of hospitalization on the periodontal status of patients admitted to a private hospital. Methods A sample of 41 patients answered a questionnaire on oral hygiene habits before and after hospitalization. An examiner measured the Periodontal Screening and Recording ratio (PSR) within 24 hours after hospitalization (T0), after five (T1) and after ten days of hospital admission (T2). Results 47 RESUMO ObjetivoAvaliar o impacto da internação hospitalar sobre a condição periodontal de pacientes em um hospital privado. MétodosA amostra de 41 pacientes respondeu questionário sobre hábitos de higiene bucal antes e após a internação. Um examinador mensurou o índice Periodontal Screening and Recording (PSR) no início, cinco e dez dias a partir da admissão hospitalar. ResultadosNenhum paciente recebeu orientação sobre higiene bucal por profissionais do hospital. Após 5 dias do exame inicial, 58,8% dos pacientes sadios apresentaram sangramento à sondagem e 16,7% dos pacientes com sangramento apresentaram cálculo dental; e 10 dias depois, 70,0% dos pacientes sadios apresentaram sangramento gengival e 57,1% daqueles que já tinham sangramento gengival apresentaram cálculo dental. Houve um aumento das necessidades de tratamento. ConclusãoA condição periodontal de pacientes internados agravou-se com o decorrer do tempo de internação e, consequentemente, houve um aumento da necessidade de tratamento. Isso desperta a atenção para a importância dos cuidados de higiene bucal no hospital.

Background: Protocadherins ( PCDHs ) have been reported as tumor suppressor genes, implying that these genes may be involved in tumor suppression in a variety of cancers. However, a thorough understanding of the functions and mechanisms of PCDHs remains limited. Our aim was to investigate the methylation profile of PCDHs in human malignant neoplasms. Methods: This systematic review has been recorded in PROSPERO (#42019117844) and conducted according to PRISMA’s checklist; search was conducted in LILACS, PubMed, Science Direct, Scopus, and Web of Science databases, manually, with search queries and without date or language restrictions. Results: We found 91 articles, of which 26 were used for this meta-analysis and categorized according to the origin of the neoplasia. In total, 3,377 cases were compiled, with PCDH10, PCDH17 , and PCDH8 being the most studied; males were 2.22 times more affected than females. Studies have shown significant heterogeneity (p <0.001), with the odds ratio varying between cases and controls [2.20 (95% CI = 1.11– 4.35) to 209.05 (95% CI = 12.64– 2,457.18)], and the value of association between methylation and cancers studied was 26.08 (95% CI = 15.42–44.13). Conclusion: In this systematic review, we have demonstrated using meta-analysis that PCDHs could emerge as potential tumor suppressor genes and that a significant increase in methylation may be useful for early detection of different cancers. This work may help in the identification of new prognostic biomarkers in malignant neoplasms.

ObjectiveTo evaluate the impact of the cost of oral hygiene products in Teresina, Piauí, on the Brazilian minimum salary (MS) over the period of two years. Methods The writer of this study visited 12 businesses from five geographical areas of the city during four consecutive months in 2011 and 2013 to collect the prices of toothbrushes, toothpaste, dental floss and mouth rinse solutions of different brands. The prices were used to calculate the monthly expense that one individual would have if they consumed the ideal quantity of the products, as recommended by the dental literature.

The objective of this case is to discuss the endodontic management in patient diagnosed with Progressive Ossificans Fibrodysplasia (POF) who sought the dental service due to discomfort in the mandible. Minor mobility of the peripheral joints, spinal involvement, gait limitation, inability to sit, report of joint pain, and limitation of TMJ movements were observed on the extra-oral examination. The intraoral examination revealed the presence of ectopic teeth (13 and 23), prolonged retention of primary teeth (53 and 63), dental gyrosurgery (34 and 33), caries lesion on teeth 36 and 47, and dental crowding. To the percussion test and the thermal pulp sensitivity of the tooth 36, there was no response, indicating pulp necrosis. Conventional endodontic therapy was performed under intrapulpal anesthesia and the dental chair placed at 45º. The patient evolved without painful symptomatology, is free of heterotopic ossification resulting from the treatment and her ability to open the mouth remained the same.