Background: A novel coronavirus COVID-19 outbreak causing infectious respiratory disorders. COVID-19 disease has no specific treatment. In the traditional medicinal system, different formulations are available for infectious diseases. Objective: This review discusses the significance and utilization of Siddha and Ayurvedic herbal formulations for COVID-19 treatment and provides scientific information regarding the phytochemistry and pharmacological profiles of Indian medicinal plants used in the formulation. Method: The information on medicine and medicinal plants was collected from research papers, review papers, and books available in several electronic databases, including Google Scholar, SpringerLink, and PubMed was explored as information sources. Results: Traditional medicinal plants are potentially used in formulations due to their inevitable therapeutic properties. Phytochemistry and pharmacological properties of medicinal plants used in the formulations served as scientific proof for traditional medicine. Conclusion: The present study explored the great importance of Siddha and Ayurvedic formulations for COVID-19 treatment. Further scientific investigations are a need to explore these formulations as widely acceptable.

: A new series of pyrano[2,3-b]quinolines were synthesized from 3-formylquinolin-2(1H)-ones via Knoevenagel condensation followed by cyclization reaction of ethyl cyanoacetate using DMSO as solvent. This methodology is a simple; clean, fast, efficient, eco-friendly, less reaction time with an improvement in the yield and purity of the product. The structures of newly synthesized compounds were confirmed by IR, NMR, Mass and elemental analysis.