SUMMARYThe glycoproteins of cells infected with herpes simplex virus I or 2 (HSV-I or HSV-2) were solubilized with non-ionic detergent NP-40 and electrophoresed in acrylamide gels. At least 12 bands containing virus glycoproteins were formed. The HSV-I glycoproteins correspond in electrophoretic mobility to structural proteins in the HSV virions and to the virus proteins in plasma membranes of infected cells. All virus glycoproteins were bound to immunoadsorbent columns made by cross-linking either homologous or heterologous antibody. Immunoadsorbent columns readily discriminated between host and virus glycoproteins. The differentiation between HSV-I and HSV-2 glycoproteins varied; the degree of specificity of the immunoadsorbent gels was related to the specificity exhibited by the antisera in neutralization tests. All immunoadsorbent antibody gels tested bound homologous glycoproteins in proportions similar to those in the input extract. Immunoadsorbent antibody gels of high specificity bound disproportionate amounts of only a few heterologous glycoproteins. Immunoadsorbent antibody gels of low specificity reacted with heterologous glycoprotein preparations as if they were a homologous preparation.
Purpose:-This paper proposes guidelines for business enterprises engaging with indigenous communities to protect their intellectual property rights, particularly indigenous art works produced for the souvenir industry. Design/methodology/approach-Literature on indigenous art and souvenirs demonstrated exploitation of indigenous communities' intellectual property was facilitated by a lack of knowledge of how to otherwise behave. The proposed guidelines for commercial entities wishing to engage ethically with indigenous communities draws on international exemplars. Findings-A twelve-point framework for ethical commerce in indigenous souvenirs between indigenous communities and businesses is proposed to ensure populations lacking economic and social power are not disenfranchised by limited experience in a market society. Social implications-The proposed guidelines contribute to achieving reconciliation between mainstream and indigenous people in various countries throughout the world. Originality / value-This paper assists development of guidelines enabling ethical decisionmaking in the souvenir industry applying a critical approach to the principles of corporate responsibility.
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