In this work, we described the development an electrochemical sensor based on electroreduction of graphene oxide (rGO) on a glassy carbon electrode (GCE) for simultaneous determination of l-Dopa and benserazide. For the elaboration of the GCE/rGO, the developed methodology was based on the electrochemical technique: multiple pulse amperometry (MPA). The MPA was more stable and efficient for the formation of rGO film, under optimum conditions (pH 6.00; concentration of rGO 2.00 mg mL −1 ; time 450 s; potentials −0.60, −0.70, −0.80, −0.90, −0.95, −1.00, −1.10, −1.20, and -1.30 V). After the film was formed, the cyclic voltammetry was used to detect LD and BZ in real samples and optimized conditions 0.05 mol L −1 PBS (pH 5.50). The linear range for the LD is 25-425 μmol L −1 and the BZ of 5-80 μmol L −1 . The limit of detection calculated was 17.10 (LD) and 2.99 (BZ) μmol L −1 .
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