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Introduction: Although, the non operative treatment modalities of degenerative spondylolisthesis remained relatively unchanged during the past two decades, the number of surgical options has increased rapidly over the same period. The optimal surgical technique to treat symptomatic spondylolisthesis has not been determined. Materials and Methods: In this prospective, non-randomizedstudy, 56 patients of degenerative spondylolisthesis who have failed to conservative treatment for a minimum period of 3 months were subjected to surgery (decompressive laminectomyplus posterolateral instrumentation with pedicle screwsplus intertransverse process arthrodesis with autologous bone graft) to compare the intensity of pain and degree of disability pre-operatively and post operatively at six months follow up using self-administered questionnaire and radiological assessment. Results: The degree of spondylolisthesis was reduced post operatively (23.11% vs15.19%; p <0.001). Pain on visual analogue scale was also reduced post operatively (7.52 ± 0.68 vs 0.30±0.74; p<0.001). Other disabilities including paresthesia(16.1% vs 1.8%), hypoesthesia (48.2% vs 32.1%), weakness (48.2% vs 28.6%), stiffness(7.1% vs 0), and urinary symptoms (12.5% vs 1.8%) were also significantly (p<0.05) reduced postoperatively. Cocnclusion: Surgical treatment including decompression,posterolateral fusion and arthrodesis offers a great benefit in degenerative spondylolisthesis.

Abstract:Background