The gold standard treatment for periprosthetic joint infections is currently a 2-stage revision procedure with the use of antibiotic beads or cement spacer. We report the case of an elderly lady who had an infected total knee replacement and underwent a prosthesis retaining procedure with the use of antibiotic loaded calcium sulphate beads (stimulan in this case). Postoperatively, she became profoundly hypercalcaemic and lethargic. After other causes were excluded, she was taken for surgical washout of the knee joint. This led to prompt normalisation of serum calcium levels and resolution of her symptoms. We recommend the need for routine pre-and postoperative serial calcium measurements when using antibiotic impregnated calcium sulphate beads and that all doctors have an increased awareness of this risk.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.