Purpose With the coronavirus disease 2019 (COVID-19) pandemic spreading across the world, protective measures for containing the virus are essential, especially as long as no vaccine or effective treatment is available. One important measure is the so-called physical distancing or social distancing. Methods In this paper, we propose an agent-based numerical simulation of pedestrian dynamics in order to assess the behavior of pedestrians in public places in the context of contact transmission of infectious diseases like COVID-19, and to gather insights about exposure times and the overall effectiveness of distancing measures. Results To abide by the minimum distance of 1.5 m stipulated by the German government at an infection rate of 2%, our simulation results suggest that a density of one person per 16m2 or below is sufficient. Conclusions The results of this study give insight into how physical distancing as a protective measure can be carried out more efficiently to help reduce the spread of COVID-19.

With the Corona Virus Disease 2019 (COVID-19) pandemic spreading across the world, protective measures for containing the virus are essential, especially as long as no vaccine or effective treatment is available. One important measure is the so-called physical distancing or social distancing. In this paper, we propose an agent-based numerical simulation of pedestrian dynamics in order to assess behaviour of pedestrians in public places in the context of contact-transmission of infectious diseases like COVID-19, and to gather insights about exposure times and the overall effectiveness of distancing measures. To abide the minimum distance of 1.5 m stipulated by the German government at an infection rate of 2%, our simulation results suggest that a density of one person per 16 m 2 or below is sufficient. The results of this study give insight about how physical distancing as a protective measure can be carried out more efficiently to help reduce the spread of COVID-19.

Crystalline particle properties, which are defined throughout the crystallization process chain, are strongly tied to the quality of the final product bringing along the need of detailed particle characterization. The most important characteristics are the size, shape and purity, which are influenced by agglomeration. Therefore, a pure size determination is often insufficient and a deep level evaluation regarding agglomerates and primary crystals bound in agglomerates is desirable as basis to increase the quality of crystalline products. We present a promising deep learning approach for particle characterization in crystallization. In an end-to-end fashion, the interactions and processing steps are minimized. Based on instance segmentation, all crystals containing single crystals, agglomerates and primary crystals in agglomerates are detected and classified with pixel-level accuracy. The deep learning approach shows superior performance to previous image analysis methods and reaches a new level of detail. In experimental studies, L-alanine is crystallized from aqueous solution. A detailed description of size and number of all particles including primary crystals is provided and characteristic measures for the level of agglomeration are given. This can lead to a better process understanding and has the potential to serve as cornerstone for kinetic studies.

With the COVID-19 pandemic, the role of infectious disease spreading in public places has been brought into focus more than ever. Places that are of particular interest regarding the spread of infectious diseases are international airport terminals, not only for the protection of staff and ground crew members but also to help minimize the risk of the spread of infectious entities such as COVID-19 around the globe. Computational modelling and simulation can help in understanding and predicting the spreading of infectious diseases in any such scenario. In this paper, we propose a model, which combines a simulation of high geometric detail regarding virus spreading with an account of the temporal progress of infection dynamics. We, thus, introduce an agent-based social force model for tracking the spread of infectious diseases by modelling aerosol traces and concentration of virus load in the air. We complement this agent-based model to have consistency over a period of several days. We then apply this model to investigate simulations in a realistic airport setting with multiple virus variants of varying contagiousness. According to our experiments, a virus variant has to be at least twelve times more contagious than the respective control to result in a level of infection of more than 30%. Combinations of agent-based models with temporal components can be valuable tools in an attempt to assess the risk of infection attributable to a particular virus and its variants.

Health monitoring of civil and industrial structures has been gaining importance since the collapse of the bridge in Genoa (Italy). It is vital for the creation and maintenance of reliable infrastructure. Traditional manual inspections for this task are crucial but time consuming. We present a novel approach for combining Unmanned Aerial Vehicles (UAVs) and artificial intelligence to tackle the above-mentioned challenges. Modern architectures in Convolutional Neural Networks (CNNs) were adapted to the special characteristics of data streams gathered from UAV visual sensors. The approach allows for automated detection and localization of various damages to steel structures, coatings, and fasteners, e.g., cracks or corrosion, under uncertain and real-life environments. The proposed model is based on a multi-stage cascaded classifier to account for the variety of detail level from the optical sensor captured during an UAV flight. This allows for reconciliation of the characteristics of gathered image data and crucial aspects from a steel engineer’s point of view. To improve performance of the system and minimize manual data annotation, we use transfer learning based on the well-known COCO dataset combined with field inspection images. This approach provides a solid data basis for object localization and classification with state-of-the-art CNN architectures.