Volumetric muscle loss (VML) is an orthopedic injury involving the loss of skeletal muscle mass and function, commonly associated with battlefield blast trauma and surgical ablations (Cross et al., 2011;Owens et al., 2007Owens et al., , 2008. Despite persistent functional deficits, which are a significant medical and quality of life issue, there are currently
The effect of direct and remote postexercise ischemic conditioning on muscle soreness and strength 24 hours after eccentric drop jumps. J Strength Cond Res 37(9): 1870-1876, 2023-Strategic limb occlusion applied after exercise may facilitate recovery, not only in directly targeted tissue but also in remote areas of the body. The purpose of this study was to determine if postexercise ischemic conditioning (PEIC) applied directly to one leg facilitated recovery in the targeted leg and the contralateral leg that did not receive direct PEIC. Twenty active men participated in a single-blind, randomized, crossover design. Subjects completed 2 paired testing sessions (PEIC and control-SHAM) that included pre-assessments and 24-hour postassessments. Each paired testing session included an eccentric drop jump task, which has been shown to increase lower-body muscle soreness and decrease strength. After each drop jump task, occlusion cuffs were immediately applied. In the PEIC session, ;198 mm Hg was applied directly to one leg (PEIC-Direct), whereas the contralateral leg received a nonphysiological stimuli of 20 mm Hg (PEIC-Remote). In the control-SHAM session, both legs directly and remotely received the 20 mm Hg pressure. Unilateral pre-assessments and 24-hour postassessments included muscle soreness using a visual analog scale and strength via peak torque assessment across the force-velocity spectrum (flexion/extension 60/60, 120/120, 180/180, 240/240, 300/300 ˚•s 21 ), and a maximal eccentric extension (30/30 ˚•s 21 ). Muscle soreness was significantly increased (p , 0.05) at 24 hours compared with pretreatment except for PEIC-Direct (1.19 6 0.78 vs. 2.32 6 1.48, p 5 0.096). Across the force-velocity spectrum, there were no significant differences observed between any associated pretest and posttest (p . 0.05). PEIC applied directly to target leg after eccentric drop jumps attenuated perceived quadriceps muscle soreness 24 hours post; however, there was no effect on muscle strength.
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