Background: Onset of G.A.D. is related with bigger excessiveness and uncontrolled worry, along with more chronic course and more severe life mutilation.Individuals suffering from G.A.D. are at high risk of bothered mental health, social functioning, and overall physical &mental well being. Limited long-term efficacy of anxiolytic drugs has shown by clinical trials but drowsiness, dependency, impaired cognition and memory and sexual dysfunction like loss of libido are common adverse side effects of these drugs. Nardostachys jatamansi is a reputed Ayurvedic herb useful for treatment of various disorders mainly central nervous disorders. Various preclinical and clinical studies had proven anxiolytic activity of Jatamansi. Hence present study is planned to assess effects of Jatamansiin Generalized Anxiety Disorder. Materials and Methods: Presentdouble-blind randomized control clinical study involves two groups with 38 subjects each. Group A (Study Group) will be treated with administration of Tab. Jatamansi in the dose of 1000 mg B.D. orally with water. Group B (Control Group)will betreated with administration of Tab. Imipramine 75 mg H.S. orallyfor 60 days. Assessment parameter will be anxiety score based on symptoms of Generalized Anxiety Disorder.   H.A.M.-A. Scale, G.A.D. – 7 Scale, Manas Bhava and Oxidative Stress. Primary outcome of study is improvement in the sign and symptoms of anxiety with reduction in anxiety scale score.

Ayurveda is an ancient system of medicine, clearly mentioned epidemic under a broad term 'Janapadodhwansa'. According to Ayurveda there are two types of Vyadhis based on causative factors which are stated in Charaka Samhita vimansthan chapter 3. Acharya Sushruta called it as Maraka and Acharya Bhela called it as Janamaar. There are four factors that has been described which are getting vitiated in Janopadodhwamsa.These are Vayu (air),Jala (water),Desha (land) and Kaala (season). Among these four factors Kaala is mainly main factor. Many of today's medical sciences coincide with some of the basic principles of Ayurveda.Today whole world is suffering from the COVID-19 pandemic.To assess the concepts of epidemiology in Ayurveda and to compare the same with recent COVID-19 pandemic, literary study of the epidemic was done thoroughly, including classical treatises like Charaka Samhita, Sushruta Samhita & modern textbooks of epidemiology. Most of the concepts of Ayurveda about Janopadodhwamsa are found relevant to current theories of pandemic/epidemic. When COVID-19 pandemic compares with Janopadodhwamsa, it shows similarity in concepts like causative factors,modes of transmission,methods of prevention of outbreaks etc.Also,control measures of COVID-19 can be compared with Hetu-viparit & Vyadhi-viparitchikitsa. The concepts described in Ayurveda regarding Janapadodhwansa are more or like the present modern concept of the pandemic or epidemic.Thus, the ancient Indian medicinal systems were well known to the fact of the epidemics & outbreaks of infectious diseases

Background -Failure to ovulate is the major problem in approximately 30% - 40% cases of female infertility. The Beeja is the core stone of the female reproductive process and absence of this factor Garbha cannot occur in spite of the proper Ritu, Kshetra and Ambu. Vagbhat stated the effect of Phalaghrita on Vandhyatva (infertility), so with an objective to study the effect of Phalaghruta in comparison with clomiphene citrate study will be carried out. Materials and methods-This Single blind(participant) randomized control clinical involves two groups with 30 subjects each. Group A (Study Group)will be treated with administration of Phala Ghritain the dose of 10 ml B.D. orally with Anupana of cow milk 100 ml. Group B (Control Group)will be treated with administration of Tab. Clomiphene citrate50 mg O.D. orally for 5 days from day 3 to 7 of Menstrual cycle.  Expected outcome - Primary outcome of study will be development of follicle and Beejotsarga (ovulation) and Secondary outcome will be conception. Conclusion- Effect of drug Phala Ghrita will be stated as per observed result.