Marine litter is a significant threat to the marine environment, human health, and the economy. In this study, beach litter surveys along Vietnamese coasts were conducted in a local context to quantify and characterize marine litter using the modified GESAMP marine litter monitoring guideline. A total of 21,754 items weighing 136,820.2 g was recorded across 14 surveys from September 2020 to January 2021. Plastic was the most abundant type of litter by both quantity (20,744 items) and weight (100,371.2 g). Fishing gear 1 (fishing plastic rope, net pieces, fishing lures and lines, hard plastic floats) and soft plastic fragments were the most frequently observed items (17.65% and 17.24%, respectively). This study not only demonstrates the abundance and composition of marine litter in Vietnam, it also provides valuable information for the implementation of appropriate preventive measures, such as the redesign of collection, reuse, and recycling programs, and informs policy and priorities, with a focus on action and investment in Vietnam. Moreover, insights from this study indicate that citizen science is a useful approach for collecting data on marine litter in Vietnam.

In order to discover new antibacterial agents, series of 2-salicyloylbenzofuran derivatives were designed, synthesized and evaluated for their antibacterial activities against three Gram-(+) strains (methicillin-sensitive Staphylococcus aureus (MSSA) ATCC 29213, methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300, and Streptococcus faecalis (S. faecalis) ATCC 29212) and one Gram-(−) strain (Escherichia coli (E. coli) ATCC 25922). The 2-salicyloylbenzofuran heterocycles were generated by Rap–Stoermer condensation of salicylaldehydes with phenacyl bromides and then converted to diverse O-ether derivatives by Williamson synthesis. The targeted products were screened for in vitro qualitative (zone of inhibition) and quantitative (MIC) antibacterial activities by agar well diffusion assay and agar dilution method. Amongst the compounds, those bearing carboxylic acid functional group were found to exhibit reasonable activity against Gram-(+) bacterial strains including S. faecalis, MSSA and MRSA with the most potent antibacterial agent 8h (MICs = 0.06–0.12 mM). Besides, the 2-salicyloylbenzofurans partly displayed inhibitory activity against MRSA with the best MICs = 0.14 mM (8f) and 0.12 mM (8h). Finally, the antibacterial results preliminarily suggested that the substituent bearing carboxylic acid group at salicyloyl-C2 and the bromine atoms on the benzofuran moiety seem to be the functionality necessary for antibacterial activities.