Cherubism is a rare hereditary fibro-osseous childhood disease characterized by bone degradation and fibrous tissue replacement at the angles of the mandible and at the tuberosity areas of the maxilla that leads to prominence of the lower face and an appearance reminiscent of the cherub's portrayal in Renaissance art. This disease has an autosomal dominant hereditary characteristic. The purpose of this report is to analyse laboratory tests, clinicopathological and radiographic features of cherubism and its intraoral manifestations in a patient during 4-years of follow-up, correlating the features observed in this case with those of the literature. Also discussed is the atypical and aggressive behaviour of this case during puberty. No known cases of cherubism involving her biological father, mother, two younger brothers or other relatives were found during the review of the patient's family medical history. The menarche of this female patient occurred when she was 11 years old.At extraoral evaluation, the expression and colour of the face were normal and the eyes did not reveal any abnormalities. At intraoral clinical examination, the absence of the lower right first and second molars and the lower left second molar with bilateral eversion of the vestibule were observed. The mucosa of the right side showed a rigid consistency, whiteness and marks made by the occlusal surfaces of antagonist teeth, but the left side displayed a normal aspect.For radiological study, lateral and panoramic radiographs and computed tomography (CT) were obtained. The images showed bilateral multilocular lesions located in the body, angle, ramus and coronoid process of mandible, not affecting the condyles. In the right side, with the absence of the lower first molar, the second molar was found dislocated to the base of the mandibular bone and the third molar was directed towards the lingual cortex and mandibular angle. Their roots were incompletely formed. In the left side, the lower second molar was located below the first molar, which presented severe resorption of the distal root. The lower third molar was floating within the lesion. The maxilla showed absence of the disease and absence of the first left and right molars (Figure 2)

Bronchial schwannomas are very rare pulmonary lesions, but its awareness is important to reach correct diagnosis and decide proper intervention. Clinical and radiological characteristics are mainly unspecific and pathological examination usually provides the definite diagnosis. In small lesions, endoscopic approach may be sufficient, but in large lesions associated with organising pneumonia surgical intervention may be required. Prognosis is typically favourable. We describe a case of a woman, aged 66 years, with productive cough and sporadic haemoptysis, dyspnoea, anorexia, excessive sweating and weight loss with 2 months evolution. CT scan showed a soft tissue dense lesion on the left hilum with 3.75 cm with 18-Fludeoxyglucose uptake. Left upper lobectomy was performed. Gross examination revealed a polypoid mass without necrosis, histologically showing cellular dense (Antoni A) and less dense (Antoni B) areas with Verocay bodies, slightly pleomorphic spindle cells, without mitotic activity and positive for S100 protein on immunohistochemistry.