Wearable integrated sensing devices with flexible electronic elements exhibit enormous potential in human–machine interfaces (HMI), but they have limitations such as complex structures, poor waterproofness, and electromagnetic interference. Herein, inspired by the profile of Lindernia nummularifolia (LN), a bionic stretchable optical strain (BSOS) sensor composed of an LN-shaped optical fiber incorporated with a stretchable substrate is developed for intelligent HMI. Such a sensor enables large strain and bending angle measurements with temperature self-compensation by the intensity difference of two fiber Bragg gratings’ (FBGs’) center wavelength. Such configurations enable an excellent tensile strain range of up to 80%, moreover, leading to ultrasensitivity, durability (≥20,000 cycles), and waterproofness. The sensor is also capable of measuring different human activities and achieving HMI control, including immersive virtual reality, robot remote interactive control, and personal hands-free communication. Combined with the machine learning technique, gesture classification can be achieved using muscle activity signals captured from the BSOS sensor, which can be employed to obtain the motion intention of the prosthetic. These merits effectively indicate its potential as a solution for medical care HMI and show promise in smart medical and rehabilitation medicine.

Flexible sensors have attracted significant attention for medical applications. Herein, an AI-assisted stretchable polymer-based (AISP) sensor has been developed based on the Beer–Lambert law for disease monitoring and telenursing. Benefiting from the use of superior polymer materials, the AISP sensor features a high tensile strain of up to 100%, durability of >10,000 tests, excellent waterproofness, and no effect of temperature (1.6–60.9 °C). Such advantages support the capability that the AISP can be flexibly pasted on the skin surface as a wearable device for real-time monitoring of multiple physiological parameters. An AISP sensor-based swallowing recognition technique has been proposed with a high accuracy of up to 88.89%. Likewise, it has been expanded to a remote nursing assistance system to meet critical patients’ physiological requirements and daily care. The hands-free communication experiment and robot control applications have also been successfully conducted based on the constructed system. Such merits demonstrate its potential as a medical toolkit and indicate promise for intelligent healthcare.

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Soft and stretchable tactile sensors have received extensive attention for their potential applications in wearables, human–robot interaction, and intelligent robots. Herein, inspired by the functions of skin somatosensory signal generation and processing, an artificial intelligence‐motivated skin‐like optical fiber tactile (SOFT) sensor is proposed. It features multifunctional touch interaction capabilities including tactile amplitude and position and tensile strain. Four fiber Bragg gratings (FBGs) are embedded in a skin‐like three‐layer laminate structure of the SOFT sensor, forming a flexible tactile sensing array with a stretchability larger than 20%. Fusing the two‐level cascaded neural network, the position and magnitude of the contact force can be distinguished simultaneously. The recognition accuracy for contact position is up to 92.41% and the error is less than 4.2% within the force range of 0–3.5 N. Several SOFT sensor‐based interactive applications including pressure password interface and music playback are achieved by combining the artificial intelligence spatiotemporal dynamic logic analysis. Furthermore, the sensor is also capable of complex scenes involving tension and tactile sensing, such as dexterous hand perception and human–robot interaction control. This work provides novel insights into artificial intelligence‐based integrated skin that shows broad promise in intelligent prosthetics and bionic robotic.

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