Since it is low in cost and low in toxicity and has good biodegradability, gas-liquid-foam three-phase flow has been widely used in industrial fire protection. Due to the different characteristics of gas, liquid, and foam, liquid precipitation is liable to occur under static conditions, resulting in unstable performance of the mixture. To improve fire extinguishing efficiency, it is of great significance to study the separation process of gas-liquid-foam. In the present study, the effects of the surface tension (range from 0.04 to 0.07) and initial liquid volume fraction (range from 0.2 to 0.5) on the gas-liquid-foam separation process are investigated with the numerical tool Fluent. The liquid volume fraction is mainly influenced by two inverse effects: (a) the transformation of liquid into foam, and (b) the liquid drainage and bursting of foam. In the separation process, the volume fraction of small foam decreases monotonically while the volume fraction of medium and large foam increases slightly. Since the volume fraction of small foam is much greater than medium and large foam and its bursting process is dominant, the liquid volume fraction presents a monotonic increasing trend. The volume of the separated liquid increases almost linearly with time at various surface tensions and initial volume fractions, and the increase rate is about 0.004. In the range of the surface tension examined, the separation process is insensitive to the surface tension, resulting in almost the same drainage time. On the other hand, the separation process depends on the initial liquid volume fraction non-monotonically; namely, when the initial volume fraction is small, with the increase of the initial volume fraction, the liquid is more easily separated from the mixture, and when the initial volume fraction is over a critical value (about 0.4), the separation process is decelerated.