This paper presents a concept of a dielectric elastomer actuator (DEA) user interface (smart button) that can sense a user’s touch and provide multi-sensory tactile and acoustic feedbacks through a single electrical input signal. The DEA relies on a multi-layer layout, in which a layer detects user-driven deformations (touches) via custom-built capacitance sensing electronics, and the remaining layers are used to provide actuation (audio-tactile feedbacks). Building upon a recently presented principle, combined tactile and acoustic feedbacks are produced by concurrently exciting different vibration modes of the same active membrane over different frequency ranges. An integrated demonstrator setup is presented, which includes a DEA, an acoustic enclosure, compact sensing and driving electronics. A characterization of the prototype is conducted, including an analysis of the sound pressure level, the force/stroke output at lower working frequencies, the ability to sense deformations with different profiles and produce combined audio-tactile outputs. Compared to previous works on multi-function DEAs, the system presented in this paper provides largely improved sensing performance (with lower working voltage) and features a deeper level of integration (with small-scale custom sensing electronics, and logics embedded onto scalable microcontrollers) and is thus specifically optimised for user-interaction applications. On this end, tests with users are presented here for the first time, which allowed evaluating the subjective perception of the interface’s feedbacks. By means of further optimisation and miniaturisation of the power/sensing electronics and structural components, the layout and multifunction DEA principle presented here might lead, in the future, to the development of DEA-based smart buttons for active surfaces, or portable/wearable user interfaces and communicators.