A copper-catalyzed three-component reaction of terminal alkynes, TsN 3 , and tertiary allylic amines is developed toward the one-pot synthesis of αallylic amidines. The product was synthesized on gram scale under 1 mol % of catalyst loading. Transformations of products into alkenyl amine and other nitrogen-containing compounds are demonstrated without any loss of stereochemical information.

Multiband terahertz (THz) detectors show great application potential in imaging, spectroscopy, and sensing fields. Thermal detectors have become a promising choice because they could sense THz radiations on the whole spectrum. This paper demonstrates the operation principle, module designs with in-depth theoretical analysis, and experimental validation of a room-temperature CMOS monolithic resonant triple-band THz thermal detector. The detector, which consists of a compact triple-band octagonal ring antenna and a sensitive proportional to absolute temperature (PTAT) sensor, has virtues of room-temperature operation, low cost, easy integration, and mass production. Good experimental results are obtained at 0.91 THz, 2.58 THz, and 4.2 THz with maximum responsivities of 32.6 V/W, 43.2 V/W, and 40 V/W, respectively, as well as NEPs of 1.28 μW/Hz0.5, 2.19 μW/Hz0.5, and 2.37 μW/Hz0.5, respectively, providing great potential for multiband THz sensing and imaging systems.

Dynamic programming is difficult to apply to large-scale Bayesian network structure learning. In view of this, this article proposes a BN structure learning algorithm based on dynamic programming, which integrates improved MMPC (maximum-minimum parents and children) and MWST (maximum weight spanning tree). First, we use the maximum weight spanning tree to obtain the maximum number of parent nodes of the network node. Second, the MMPC algorithm is improved by the symmetric relationship to reduce false-positive nodes and obtain the set of candidate parent-child nodes. Finally, with the maximum number of parent nodes and the set of candidate parent nodes as constraints, we prune the parent graph of dynamic programming to reduce the number of scoring calculations and the complexity of the algorithm. Experiments have proved that when an appropriate significance level α is selected, the MMPCDP algorithm can greatly reduce the number of scoring calculations and running time while ensuring its accuracy.

The cascade of Ir-catalyzed enantioselective allylic amination and Cu-catalyzed alkyne–azide cycloaddition was designed for the asymmetric synthesis of homoallylic amidines. The nucleophilic addition of an in situ-generated enantioenriched tertiary allylamine to a ketenimine intermediate triggers a rapid and stereospecific zwitterionic aza-Claisen rearrangement in a 1,3-chiral transfer manner. The approach allows modular access to enantioenriched α-chiral homoallylic amidines in high yields with a high level of enantiomeric purity.