Background: Patients with violent behaviors have the potential to harm themselves, others, and their environment. The management of patients with violent behavior needs to consider various aspects, one of which is patients' spiritual aspect. Combining a spiritual therapy of listening to Qur'an recitation, acupressure, and using a new innovation of a calming bed during the intervention is expected to increase the effect of relaxation and patients' comfort to optimize the intervention outcomes, namely to reduce aggression level in patients with violent behaviors. Objective: This study aimed to determine the effect of the combined intervention of listening to Qur'an recitation (murottal), acupressure, and using a calming bed on reducing the Positive and Negative Syndrome Scale -Excited Component (PANSS-EC) scores in patients with violent behaviors. Methods: This study used a pre-post test quasi-experimental design without a control group. A total of 50 respondents who agreed to participate in the therapy entirely were randomly recruited. The therapy was given four times with a duration of 30 minutes each. The paired t-test was performed to find out the effect of the intervention. Results: The results showed a significant effect of the intervention on reducing the PANSS-EC score among patients with violent behavior (p=0.000). Conclusion: The combination intervention of listening to Qur'an recitation, acupressure, and use of calming beds can reduce symptoms of violent behaviors by decreasing the PANSS-EC scores. This study suggests using spiritual intervention to help patients with violent behaviors reduce their aggression.