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This paper deals with the design, simulation and control of a new lightweight hybrid Mock-Loop (MCL) concept. The proof of concept is evaluated by two simulation approaches. First, the design parameters are chosen by an optimal control problem. Second, a cascading controller structure is evaluated in a simulation. Both show that with a suitable range of the design parameter the new lightweight concept can be used as a MCL. To validate these findings, further investigations with the MCL under realistic test conditions are required.

This paper presents an optimization-based control scheme for a novel left ventricular assist device. This cardiac support system consists of two pumps connected in series and a buffer reservoir in between them. This novel concept for relieving the left ventricle is designed to allow the pre- and afterload on the heart to be explicitly adjusted and independently of each other. The first pump controls the preload of the heart with a known physiological controller. With an iterative model-based optimization, the afterload is minimized by the second pump while complying with all constraints. The proof of the control concept and a comparison to the classical single pump left-sided cardiac support is performed on a hardware-in-the-loop test bench. The results show that with the new left ventricular assist device concept, the afterload can be reduced compared to the classical cardiac support.

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