Climate change has been reported as a driver for emerging food and feed safety issues worldwide and its expected impact on the presence of mycotoxins in food and feed is of great concern. Aflatoxins have the highest acute and chronic toxicity of all mycotoxins; hence, the maximal concentration in agricultural food and feed products and their commodities is regulated worldwide. The possible change in patterns of aflatoxin occurrence in crops due to climate change is a matter of concern that may require anticipatory actions. The aim of this study was to predict aflatoxin contamination in maize and wheat crops, within the next 100 years, under a +2 °C and +5 °C climate change scenario, applying a modelling approach. Europe was virtually covered by a net, 50 × 50 km grids, identifying 2254 meshes with a central point each. Climate data were generated for each point, linked to predictive models and predictions were run consequently. Aflatoxin B 1 is predicted to become a food safety issue in maize in Europe, especially in the +2 °C scenario, the most probable scenario of climate change expected for the next years. These results represent a supporting tool to reinforce aflatoxin management and to prevent human and animal exposure.Climate change has been reported as a driver for emerging food and feed safety issues worldwide [1][2][3][4] .The expected impact of climate change on the presence of mycotoxins in food and feed is of great concern. These fungal metabolites are important causes of chronic toxicity from exposure via food 5,6 ; in particular, aflatoxins, which have the highest acute and chronic toxicity of all mycotoxins 7 . Hence, the maximal concentration of aflatoxins in agricultural food and feed products and their commodities is regulated worldwide, with specific restrictions in Europe (Commission Regulation EU/574/2011, 2006/1881/EC and amendments). The possible change in patterns of aflatoxin occurrence in food and feed crops due to climate change is a matter of concern that may require anticipatory actions.Crop growth and its interaction with beneficiary and pathogenic and/or toxigenic microorganisms vary from year to year, mainly depending on local weather, making the agricultural sector particularly exposed to climate change 8 . The topic is of great economic and societal interest both for the quantitative and qualitative effects on crop yield and the impact on the occurrence of mycotoxins 9 .Around nine million hectares of maize and 26 million hectares of common wheat are yearly grown in Europe, and cereals in general contribute to approximately 30% of the human diet of industrialised countries (data from FAOStat http://faostat3.fao.org/home/E), as well as to roughly 50% of the animal feed in Europe (European Commission, Agricultural and Rural Development, Short term outlook, 2015). Therefore, any problem related to food and feed crops is of great economic and health concern.The most toxic mycotoxins are aflatoxins, which can occur in host crops infected by some species of Aspergillus. Aflatoxins are...

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