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Objective To compare procedural and in-hospital outcomes of patients undergoing sutureless (Perceval, Livanova PLC, London, UK) and rapid deployment (Intuity Elite, Edwards Lifesciences, Irvine, USA) aortic valve replacement (group 1) versus sutured aortic valve replacement (group 2). Methods Patients receiving isolated aortic valve replacement between 2014 and 2020 were analysed using data from the Sutureless and Rapid Deployment International Registry. Patients in group 1 and group 2 were propensity-score matched in a 1:1 ratio. Results A total of 7708 patients were included in the study. After matching, 2 groups of 2643 each were created. Patients in group 1 were more likely to undergo minimally invasive approaches and were associated with shorter operative times when compared with group 2. Overall in-hospital mortality was similar between groups. While an increased risk of stroke was observed in group 1 in the first study period (2014–2016) (relative risk 3.76, p < 0.001), no difference was found in more recent year period (relative risk 1.66, p = 0.08)(p for heterogeneity 0.003). Group 1 was associated with reduced rates of postoperative low cardiac output syndrome, atrial fibrillation and mild aortic regurgitation. New pacemaker implant was three-fold higher in group 1. Conclusions Our findings showed significant differences in procedural and clinical outcomes between the study groups. These results suggest that sutureless and rapid deployment aortic valve replacement should be considered as part of a comprehensive valve program. The knowledge of the respective post-aortic valve replacement benefits for different valve technologies may result in patient-tailored valve selection with improved clinical outcomes.

European Journal of Breast Health (Eur J Breast Health) is an international, scientific, open access periodical published by independent, unbiased, and double-blinded peer-review principles. It is the official publication of the Turkish Federation of Breast Diseases Societies, and Senologic International Society is the official supporter of the journal.

Background Left ventricle (LV) lipoma is a very rare, benign cardiac tumor. Due to its rarity, LV lipoma is often misdiagnosed. Aspecific symptoms such as murmurs, arrhythmias, memory loss and palpitation may occur due to the mass effect. Case presentation We report a case report of a 42 year old woman who was found to have left ventricle mass after check-up for arrhytmia. By a fully endoscopic approach, the mass was successfully resected from the left ventricle without the need for sternotomy. Conclusion Total endoscopic removal of left ventricle lipoma’s can be done safely and has several advantages to conventional sternotomy. Larger studies are needed to confirm this hypothesis.

Objective We present the long term results of a trileaflet (Triflo) vs. bileaflet (On-X) mechanical valve in both aortic and pulmonary position in a sheep model. Methods The Triflo valve was implanted in 21 female sheep in aortic (n = 8) and pulmonary position (n = 13). The On-X valve was implanted in 7 female sheep in aortic (n = 1) and pulmonary (n = 6) position. No antithrombotic medication of any kind was given postoperatively. In the aortic group, survival cohorts were 3 and 5 months. In the pulmonary group, survival cohorts were 10 and 20 weeks. Valve performance was assessed using hematology, echocardiography and acoustic measurements combined with postmortem pathology analysis of the downstream organs. Results Mean gradients were lower for the Triflo valve in both pulmonary (4,30 mmHg (3.70-5.73) vs. 6.80 mmHg (4.63-7.96), p = 0.012) and aortic (5.1 mmHg (4.2-7.7) vs. 10.7 mmHg (8.7-12.9), p = 0.007) position. Peak gradients were lower for the Triflo-valve in both pulmonary (8.05 mmHg (6.75-10.23) vs. 13.15 mmHg (9.20-14.76), p = 0.005) and aortic (8.7 mmHg (7.5-12.5) vs. 16.5 mmHg (14.2-19.6), p = 0.009) position. In both positions, leaflets and housing surface were free from any deposits macro- and microscopically and comparable to nonimplanted control valves. Peripheral organs showed no signs of thrombo-embolic damage. Biochemical and hematological were comparable to preoperative. The closing click sound pressure level (SPL) of the Triflo was significantly lower in both aortic (108.4 SPL (102.0-115.7) vs. 111.7 SPL (105.5-117.0), p < 0.001) and pulmonary (103.6 SPL (99.1-108.9) vs. 118.5 SPL (116.7-120.2), p < 0.001) position. Conclusions Preliminary in vivo results of the Triflo valve are promising in both aortic and pulmonary position in an ovine model. Excellent hemodynamics, stable long term function, low valve noise and no thromboembolic events in the absence of antithrombotic medication lay the foundation to a future clinical first-in-man trial.