We experienced the case of Low-grade appendiceal mucinous neoplasm treated with laparoscopic management, which was originally diagnosed as a right cystic adnexal mass. The case involved an 81-year old woman had undergone a total abdominal hysterectomy for leiomyoma of the uterus when she was 48 years old. She was refered to our hospital after being diagnosed with a cystic lesion of the pelvis at a local internal medicine clinic, with a dull pain in her right lower abdomen. We suspected a right ovarian cyst, but no conclusive evidence was found, so we performed exploratory laparoscopic operation. We found that the uterus and both adnexa had been extracted, and the cyst was derived from appendix, so we performed appendectomy. We made the diagnosis of a Low-grade appendiceal mucinous neoplasm after pathological examination. Cystic disease in the female pelvis is common. The majority of cystic pelvic masses originate in the ovary, but some other pelvic organs mimic this anomaly. It is important to understand the relationship of the cyst with its anatomic location, to identify normal ovaries at imaging, and to compare the findings with a patient's clinical history to avoid misdiagnosis.
Malignant ovarian steroid cell tumours are a rare subgroup of sex cord-stromal tumours. There are no systematic reviews on the associated treatments, and little is known about their genomic profile. We describe a case of a pelvic malignant ovarian steroid cell tumour in a premenopausal woman in her 40s. She received cytoreductive surgery and six cycles of paclitaxel+carboplatin+bevacizumab. After recurrence, the tumour was surgically removed again, followed by radiation and hormone blockade therapy. Complete remission was achieved after treatment with bleomycin, etoposide and cisplatin. She remained in a platinum-sensitive relapse state and subsequently received maintenance therapy with olaparib. Since the tumour was initially refractory to treatment, tissue specimens were screened for gene mutations using a next-generation sequencing oncology panel and a somatic variant detection system, which revealed somatic gene mutations in ARID1A, PIK3CA, TERT and ATM, some of which are involved in DNA repair.
Retained placenta, a partial retention of placental tissue after abortion or delivery, may cause massive hemorrhage. When it is removed surgically with uterine preservation, uterine artery embolization is often performed beforehand to reduce the amount of bleeding during operation. However, the risk of postoperative obstetrical complications is concerning due to the extended amount of time with blood flow blocked in the uterine artery. A 37-year-old woman, gravid 5 para 3, came to our hospital on the 35 th postpartum day because of bloody vaginal discharge after artificial abortion at 19 weeks of gestation by gemeprost vaginal suppository. An intrauterine mass with abundant blood flow was observed by ultrasound. The elevated level of serum human chorionic gonadotropin (HCG) was 26.9 mIU/ml, and was indicative of retained placenta. Hysteroscopic resection after temporal laparoscopic uterine artery clipping was performed for the removal of retained placenta without any complications. We report here this minimally invasive procedure for the treatment of retained placenta and discuss its efficacy, usefulness and safety.
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