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Anti‐acetylcholine receptor antibody (AChR Ab) plays an important role in the pathogenesis of myasthenia gravis (MG). We investigated the change of anti‐AChR Ab titer after thymectomy of 10 MG patients including five patients whose age at onset was younger than 16 years. Anti‐AChR Ab titer was increased in four of six patients with remission and three of four patients without remission. Change of anti‐AChR Ab titer in individual patients showed an increase occurred 1–4 years after thymectomy. It is likely that thymectomy influences immune response and induces autoreactive lymphocytes and autoantibodies.

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