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Background and Objectives: To analyze histopathological changes and degree of damage to the axillary tissue due to single-and double-pass irradiation therapy using a microwave energy-based device. Study Design/Materials and Methods: We included 15 axillary hyperhidrosis and axillary osmidrosis patients who received microwave irradiation therapy between March 2017 and March 2019. Ten patients underwent single-pass irradiation and five underwent double-pass irradiation, after which skin samples were collected from the right and left axillae for pathological analysis. Samples were taken in a consistent manner from Patient 6 onwards and a comparative study of five single-pass and five double-pass patients was conducted (n = 10). Results: Histopathological analysis showed destruction and fibrosis in addition to necrosis and damage to the adipose tissue in apocrine and eccrine sweat glands. In the superficial microvasculature, blood vessel wall damage and thrombus formation were observed as well as damage in the hair follicles and hair bulbs. No obvious damage was observed in the epidermis and nerves. The amount of damage to sweat glands was higher in patients undergoing double-pass instead of single-pass irradiation. Conclusion: From a histopathological point of view, microwave energy-based irradiation therapy can be considered efficient, as there was no damage to epidermis and nerves and favorable destruction of apocrine and eccrine glands. As the amount of damaged sweat glands was higher after double-pass irradiation, it can be considered more effective than single-pass irradiation. Lasers Surg. Med.

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The objective of this study was to examine the postoperative taste sensation in patients with carcinoma of the tongue who underwent tongue reconstruction after subglossectomy.Patients and Methods : Eleven patients, aged 43 to 76 years with an average of 58.7 years, consisting of 9 men and 2 women, were enrolled in this study. Examination results based on the paper disk method were evaluated at the posterior wall of the mid pharynx and retained tongue by a 6-grade rating scale.Results : All the patients but one had taste disorders. Surprisingly, taste sensation at the posterior wall of the mid pharynx was better than that on the remaining tongue.Conclusion : Carcinoma of the tongue involves several factors which cause taste disorders, including preoperative chemotherapy, surgical invasion and zinc deficiency caused by postoperative eating disorders. After subglossectomy, the patients could sense the taste by taste buds distributed in the pharynx. Taste disorders might occur due to preoperative chemotherapy and zinc deficiency.