We aimed to establish an ion channel measurement system using a charge transfer type ion image sensor on which an artificial lipid bilayer membrane was formed. A supported lipid bilayer (SLB) was formed on the K + -sensitive membrane composed of polyvinyl chloride on the ion image sensor. Fluid SLB fully covered the sensor surface and consequently reduced the output potential of the ion sensor, keeping the Nernst response of the ion sensor. We measured the time course after changing K + concentrations before and after the formation of a SLB. The temporal response of the output potential was decelerated after the SLB formation, because ion diffusion to the sensor surface was shielded by the SLB. We demonstrated the ion channel reconstruction and inhibitor addition using gramicidin and Ca 2+ .
The powder-in-tube method using an Ag sheath is applied to achieve high current capacity in the tapes of Bi-Pb-Sr-Ca-Cu-O (BPSCCO) with the high-Tc phase (Tc=110 K), by a combination process of cold working and sintering. Two kinds of the BPSCCO powder with and without Ag doping are used as the materials for tape fabrication. The morphology, structure, and critical current density Jc are investigated on the tapes by x-ray diffraction, differential thermal analysis, scanning electron microscope, magnetic susceptibility, and I-V curves. The optimum sintering conditions to obtain a maximum in the value of Jc at 77 K and 0 T are presented in the Ag-doped tapes and the nondoped ones. An improvement in the Jc vs B properties up to 1 T at 77 K is presented in the BPSCCO tape by Ag doping. The Ag doping causes neither change in the value of Tc (=110 K) nor decomposition of the high-Tc phase.
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