Since July 2020, or around six months after the outbreak of the new corona virus infection in 2019, no one has been able to explain why people with HIV (PLWH) are negatively affected (COVID-19). COVID-19 vulnerability appears to be the same in HIV-positive and HIV-negative individuals, however results may be inconsistent. Some of the misunderstandings are due to the lack of data and the novelty of COVID-19, while others are due to the ambiguity of the question "when?" It has the means to make HIV a "risk factor" for the development of COVID-19.