Objective: To compare the role of beta and A point-nasion-B (ANB) angles in evaluating the sagittal skeletal discrepancy in a cephalometric study done in the Pakistani population. Study Design: Comparative cross-sectional study. Place and Duration of Study: Orthodontics Department, Armed Forces Institute of Dentistry, Rawalpindi Pakistan, from Jul to Dec 2019. Methodology: A total of 150 subjects between the age of 18 to 25 years were enrolled in the study A point-nasion-B angle was measured using the lateral cephalogram in all the subjects and was divided into classes I, II and III. Beta angle was also measured in all the patients. Results: Out of 150 subjects, 92 (61.3%) patients were males, and 58 (38.7%) were females. The mean age of the subjects was 19.2 ± 2.138 years. 89 (59.3%) patients were classed in Class-I, 40 (26.7%) in class-II and 21 (14%) in class-III. The mean score of A point-nasion-B angles among the patients was 7.5 ± 1.112. The mean score for beta angles in the study participants was 30.5 ± 2.214. A point-nasion-B and beta angles both had a significant relationship with classes of skeletal discrepancies. Conclusion: Sagittal skeletal discrepancies can be evaluated with accuracy by using both A point-nasion-B and beta angles. Lateral cephalograms and radiography measures emerged as reliable techniques to classify the patients in various skeletal patterns. Factors like age and gender do not influence skeletal discrepancies.