able because the patients is a poor surgical risk, TAE has To assess intrahepatic metastasis (IM) and multicenbeen considered the treatment of choice. However, the value tric occurrence (MO) after initial treatment of small heof TAE is limited if the small HCCs have intracapsular or patocellular carcinomas (HCC) ß 2 cm in diameter, we extracapsular invasion. performed clinical and pathological studies in 112 pa-PEIT has been shown to be highly effective in patients with tients who underwent percutaneous ethanol injection HCCs ß3 cm in diameter. with HCC were admitted to Ogaki Municipal Hospital, and 163 of the 750 were found to have an HCC ß2 cm in diameter. One hundred and twelve of these patients who had undergone PEIT or hepatic Hepatocellular carcinoma (HCC) is one of the most maligresection were selected for this retrospective study. All cases were nant neoplasms in Japan. Because of recent progress in the diagnosed histologically. Fifteen patients were diagnosed by specific development of new diagnostic modalities, the incidence of imaging diagnosis (histological confirmation was made by analysis detection of small HCCs has increased.1-4 Therapeutic ap-of specimens obtained at surgery) and 97 patients were diagnosed proaches to HCC also have progressed markedly in recent by percutaneous liver tissue core biopsy with ultrasound guidance. years through the development of hepatic resection, trans-The PEIT was performed according to previously published methcatheter arterial embolization, and percutaneous ethanol in-ods 24 in 82 patients who had not undergone surgery because of imjection therapy (PEIT). [5][6][7] The surgical resectability rate of paired liver function or who had requested this type of therapy.Briefly, after administration of a local anesthetic, the needle was HCC, however, has remained low, this is, because most pa- A 25 ). In this series, radical hepatectomy represented the removal of Received December 29, 1995; accepted September 25, 1996. all tumors from the liver. and/or helical with contrast medium were performed every 3 months.

able because the patients is a poor surgical risk, TAE has To assess intrahepatic metastasis (IM) and multicenbeen considered the treatment of choice. However, the value tric occurrence (MO) after initial treatment of small heof TAE is limited if the small HCCs have intracapsular or patocellular carcinomas (HCC) ß 2 cm in diameter, we extracapsular invasion. performed clinical and pathological studies in 112 pa-PEIT has been shown to be highly effective in patients with tients who underwent percutaneous ethanol injection HCCs ß3 cm in diameter. with HCC were admitted to Ogaki Municipal Hospital, and 163 of the 750 were found to have an HCC ß2 cm in diameter. One hundred and twelve of these patients who had undergone PEIT or hepatic Hepatocellular carcinoma (HCC) is one of the most maligresection were selected for this retrospective study. All cases were nant neoplasms in Japan. Because of recent progress in the diagnosed histologically. Fifteen patients were diagnosed by specific development of new diagnostic modalities, the incidence of imaging diagnosis (histological confirmation was made by analysis detection of small HCCs has increased.1-4 Therapeutic ap-of specimens obtained at surgery) and 97 patients were diagnosed proaches to HCC also have progressed markedly in recent by percutaneous liver tissue core biopsy with ultrasound guidance. years through the development of hepatic resection, trans-The PEIT was performed according to previously published methcatheter arterial embolization, and percutaneous ethanol in-ods 24 in 82 patients who had not undergone surgery because of imjection therapy (PEIT). [5][6][7] The surgical resectability rate of paired liver function or who had requested this type of therapy.Briefly, after administration of a local anesthetic, the needle was HCC, however, has remained low, this is, because most pa- A 25 ). In this series, radical hepatectomy represented the removal of Received December 29, 1995; accepted September 25, 1996. all tumors from the liver. and/or helical with contrast medium were performed every 3 months.

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