No abstract

Since particle beam distribution is vulnerable to change in bowel gas because of its low density, we developed a deep neural network (DNN) for bowel gas segmentation on X-ray images. We used 6688 image datasets from 209 cases as training data and 102 image datasets from 51 cases as test data. For the training data, we prepared three types of digitally reconstructed radiographic (DRR) images (alldensity, bone and gas) by projecting the treatment planning CT image data. However, the real X-ray images acquired in the treatment room showed low contrast that interfered with manual delineation of bowel gas. Therefore, we used synthetic X-ray images converted from DRR images in addition to real Xray images. We evaluated DNN segmentation accuracy for the synthetic X-ray images using Intersection over Union (IoU), recall, precision, and the Dice coe cient, which measured 0.708 ± 0.208, 0.832 ± 0.170, 0.799 ± 0.191, and 0.807 ± 0.178, respectively. The evaluation metrics for the real X-images were less accurate than those for the synthetic X-ray images (0.408 ± 0237, 0.685 ± 0.326, 0.490 ± 0272, and 0.534 ± 0.271, respectively). Our DNN appears useful in increasing treatment accuracy in particle beam therapy.

Since particle beam distribution is vulnerable to change in bowel gas because of its low density, we developed a deep neural network (DNN) for bowel gas segmentation on X-ray images. We used 6688 image datasets from 209 cases as training data and 102 image datasets from 51 cases as test data. For the training data, we prepared three types of digitally reconstructed radiographic (DRR) images (all-density, bone and gas) by projecting the treatment planning CT image data. However, the real X-ray images acquired in the treatment room showed low contrast that interfered with manual delineation of bowel gas. Therefore, we used synthetic X-ray images converted from DRR images in addition to real X-ray images. We evaluated DNN segmentation accuracy for the synthetic X-ray images using Intersection over Union (IoU), recall, precision, and the Dice coefficient, which measured 0.708 ± 0.208, 0.832 ± 0.170, 0.799 ± 0.191, and 0.807 ± 0.178, respectively. The evaluation metrics for the real X-images were less accurate than those for the synthetic X-ray images (0.408 ± 0237, 0.685 ± 0.326, 0.490 ± 0272, and 0.534 ± 0.271, respectively). Our DNN appears useful in increasing treatment accuracy in particle beam therapy.