Ischemic preconditioning (IPC) improves maximal exercise performance. However, the potential mechanism(s) underlying the beneficial effects of IPC remain unknown. The dynamics of pulmonary oxygen uptake (VO2) and muscle deoxygenation during exercise is frequently used for assessing O2 supply and extraction. Thus, this study examined the effects of IPC on systemic and local O2 dynamics during the incremental step transitions from low- to moderate- and from moderate- to severe-intensity exercise. Fifteen healthy, male subjects were instructed to perform the work-to-work cycling exercise test, which was preceded by the control (no occlusion) or IPC (3 × 5 min, bilateral leg occlusion at >300 mmHg) treatments. The work-to-work test was performed by gradually increasing the exercise intensity as follows: low intensity at 30 W for 3 min, moderate intensity at 90% of the gas exchange threshold (GET) for 4 min, and severe intensity at 70% of the difference between the GET and VO2 peak until exhaustion. During the exercise test, the breath-by-breath pulmonary VO2 and near-infrared spectroscopy-derived muscle deoxygenation were continuously recorded. Exercise endurance during severe-intensity exercise was significantly enhanced by IPC. There were no significant differences in pulmonary VO2 dynamics between treatments. In contrast, muscle deoxygenation dynamics in the step transition from low- to moderate-intensity was significantly faster in IPC than in CON (27.2 ± 2.9 vs. 19.8 ± 0.9 sec, P < 0.05). The present findings showed that IPC accelerated muscle deoxygenation dynamics in moderate-intensity exercise and enhanced severe-intensity exercise endurance during work-to-work test. The IPC-induced effects may result from mitochondrial activation in skeletal muscle, as indicated by the accelerated O2 extraction.

Ischemic preconditioning (IPC) enhances whole-body exercise endurance. However, it is poorly understood whether the beneficial effects originate from systemic (e. g., cardiovascular system) or peripheral (e. g., skeletal muscle) adaptations. The present study examined the effects of IPC on local muscle endurance during fatiguing isometric exercise. 12 male subjects performed sustained isometric unilateral knee-extension exercise at 20% of maximal voluntary contraction until failure. Prior to the exercise, subjects completed IPC or control (CON) treatments. During exercise trial, electromyography activity and near-infrared spectroscopy-derived deoxygenation in skeletal muscle were continuously recorded. Endurance time to task failure was significantly longer in IPC than in CON (mean±SE; 233±9 vs. 198±9 s, P<0.001). Quadriceps electromyography activity was not significantly different between IPC and CON. In contrast, deoxygenation dynamics in the quadriceps vastus lateralis muscle was significantly faster in IPC than in CON (27.1±3.4 vs. 35.0±3.6 s, P<0.01). The present study found that IPC can enhance muscular endurance during fatiguing isometric exercise. Moreover, IPC accelerated muscle deoxygenation dynamics during the exercise. Therefore, we suggest that the origin of beneficial effects of IPC on exercise performance may be the enhanced mitochondrial metabolism in skeletal muscle.

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For stable gait generation on the level floor, restoring mechanical energy lost by heel-strike collision at the ground is necessary. Parametric excitation principle is one of the solutions. Harata et al. applied this principle to a knee actuated robot to achieve parametric excitation by bending and extending the knee, and succeeded in generating a sustainable biped gait by computer simulation. Although only the dynamics of the swing-leg was considered in the method, the stance-leg's dynamics also affects the swing-leg's dynamics. Therefore we considered the whole dynamics of the robot in this paper. Therefore, we dealt with the robot's center of mass as an inverted pendulum and achieved stable gait generation by parametric excitation of the inverted pendulum. The resultant energy efficiency was increased significantly.

Joint kinetic characteristics during the eccentric phase are important in resistance exercises because eccentric actions with elastic potential energy storage lead to the energy recoil with large joint moment and power generation during the subsequent concentric phase. Previous studies assessed the force production capacity in the barbell hip thrust; however, these were reported by the methodology using only surface electromyographic amplitudes recorded in the lower back and thigh muscles and did not focus on eccentric action. This study aimed to determine kinetic characteristics of lumbosacral, hip and knee joints of sprinters during the eccentric and concentric phases in a barbell hip thrust, compared to those of deadlift and back squat. Eleven well-trained male sprinters participated in this study. Each participant performed two full ranges of motion repetition using their previously determined six-repetition maximum loads. During strength exercises, reflective marker displacements attached to the body and a barbell were captured using 22 high-speed cameras, and ground reaction forces were captured using 4 force plates simultaneously. In the barbell hip thrust, as well as deadlift, the peak values of the lumbosacral and hip extension moments were generated almost immediately after the eccentric phase and were 24% and 42% larger than those in the back squat, respectively. In the knee joint, the largest was the peak extension moment in the back squat (155 ± 28 Nm), followed in order by that in the barbell hip thrust (66 ± 33 Nm) and that in the deadlift (24 ± 27 Nm). These demonstrated that a barbell hip thrust, as well as deadlift, can be a resistance exercise to strengthen the lower back and posterior thigh muscles. Thus, these resistance exercises may be able to be used separately according to their intended purposes, enabling transformations of strength training to specific dynamic motions such as sprint running.