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Hidradenocarcinoma: A Sinister Diagnosis of a Suspected Benign ConditionEccrine glands are sweat glands located in the palms and soles, head, trunk, and extremities. Eccrine carcinoma presents with four types of histology, namely eccrine porocarcinoma, syringoid eccrine carcinoma, mucinous eccrine carcinoma, and clear cell hidradenocarcinoma. Malignant carcinomas of these glands are very rare and occur in one in 13,000 (0.005%). 1 Clear cell hidradenocarcinoma (CCH) was first reported as clear-cell eccrine carcinoma by Keasby and Hadley in 1954. In 1992, The American Joint Committee on Cancer categorized clear CCH as a superficial malignancy and applied the TNM staging system. It has been given several names in the literature like malignant clear cell myoepithelioma, malignant clear cell acrospiroma, clear cell eccrine carcinoma, and malignant clear cell hidradenoma. CCH is usually found associated with hidradenoma, which is differentiated only by its malignant cytoarchitectural features from its benign counterpart, although it can occur de novo as well. Generally, they occur in patients in their fourth decade or older, grows slowly, and can present for several years without apparent change. There can be a heterogenous group of lesions from low-grade, well differentiated to high-grade, poorly differentiated tumors with the potential for repeat local recurrence and distal metastasis. A recurrence rate of hidrad enoccur cinoma has been described to be 10 per cent, which can occur with or without complete excision of tumor. 2 Metastasis appear first in regional lymph nodes, although the most common hematogenic metastases appear in lungs.A 90-year-old man presented with a slowly growing, 2.5-cm cyst on his right calf causing him mild discomfort. On examination, it was found to be firm and cystic, consistent with a diagnosis of a sebaceous cyst.