Detection thresholds were obtained for a 2 degrees Gaussian-blurred spot flashed for 200 ms on an 8.9 degrees white adapting field of 1070 trolands. The spot's contrast was represented in an L-, M-, and S-cone contrast space. Detection thresholds were obtained for many vectors close to specific but theoretically important planes within this space. A three-dimensional surface was fitted to the data generated by the probability summation of three mechanisms, each a weighted sum of cone contrasts. The fit revealed a red-green chromatic mechanism driven by delta L/L--delta M/M with no S-cone input that was 1 order of magnitude more sensitive than the two other mechanisms. The latter consisted of a luminance mechanism with little S-cone input and a blue-yellow chromatic mechanism with the S cone opposed to L and M cones.

Background: There are conflicting reports concerning the ability of people with migraine to

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Color, independent of luminance or particular color contrasts, can have therapeutic effects for people with visually triggered migraine as it can reduce the number of perceived illusions when viewing stripes or text. The effect was not color-specific and was greatest for the 12 cpd gratings. Given the significant associations between the achromatic discomfort measures and reports of visual triggers, and the lack of significant associations between the chromatic discomfort measures and reports of visual triggers, further research is recommended to explore the potential to reduce the number of visually triggered migraines with color in addition to alleviating visual discomfort.