Stroke is the second leading cause of death and the third leading cause of disability, whose incidence increase with hypertension. Various antihypertensives are used as secondary therapy for stroke. However, the effectiveness of each drug is still debated. This study aims to determine the correlation between various types of antihypertensive drugs on the incidence of acute stroke. This research is a cross-sectional study. Inclusion criteria included hypertensive patients who had used antihypertensive drugs for at least a year and were aged 36. We included 78 subjects, 47 men and 31 women. The drugs were ACEI + CCB (13), ARB (8), ARB + CCB (22), and CCB (35). The subject had an ischemic stroke (8) and a hemorrhagic stroke (1). The logistic regression test showed ACEI + CCB as a reference category. The result consecutively showed ARB (OR, 4.95; CI, 0.72 to 33.89; p = 0.103), CCB (OR, 2.61; CI, 0.39 to 17.01; p = 0.317), and ARB + CCB (OR, 2.36; CI, 0.19 to 29.75; p = 0.507). The antihypertensive drugs had no significant correlation with the incidence of acute stroke. It indicated that stroke risk was not triggered by antihypertensive and could effectively control hypertension and protect patients against stroke

Background: Dysmenorrhea or pain during menstruation is due to excessive contractions during the sloughing of the uterine wall with symptoms of cramping pain in the lower abdomen. The incidence of primary dysmenorrhea in Indonesia is 54.89%. However, many teenagers do not know how to manage the pain. The pharmacological therapy of dysmenorrhea includes painkillers and anti-prostaglandin, while the non-pharmacological approach includes distraction therapy. One of the distraction therapy that is easy to do is murottal Al-Qur’an.Objective: This study observed the role of listening to murottal Al-Qur’an on the intensity of dysmenorrhea among senior high school students.Methods: The design of this study is a quasi-experimental pretest-posttest with a control group design. There were 100 subjects aged 15-18 years old. The sampling technique applied purposive sampling. Data analysis of this study applied Wilcoxon, Mann-Whitney, relative risk (RR), and number needed to treat (NNT) test.Results: The mean pain level in the experimental and control group were 5.42 and 5.56 before intervention. After therapy, the pain level decreased to 2.86 and 5.30 in the experimental and control group, respectively. There was a significant difference in the pain level before and after in the experiment group (p <0.001). Relative risk showed that murottal intervention decreases the pain level by 3.267 times. NNT of the study was 1.467.Conclusion: Murottal Al-Qur’an significantly reduced the degree of pain with a p-value <0.001

Latar Belakang: Rhinitis alergi (RA) adalah penyakit saluran napas atas yang disebabkan oleh reaksi inflamasi yang diperantarai IgE setelah adanya pajanan alergen. Uji cukit kulit merupakan tes standar yang digunakan dalam menegakkan diagnosis RA. Uji cukit kulit memberikan informasi keberadaan IgE spesifik terhadap protein dan peptide antigen atau yang dikenal dengan alergen.Tujuan: Mengetahui gambaran hasil pemeriksaan uji cukit kulit pada mahasiswa fakultas kedokteran Universitas Muhammadiyah Yogyakarta dengan gejala rhinitis alergi.Metode penelitian: Deskriptif melalui metode potong lintang.Hasil: Sebanyak 28 orang dengan gejala rhinitis alergi telah menjalani pemeriksaan uji cukit kulit. dengan jenis kelamin perempuan sebanyak 21 orang, laki-laki sebanyak 7 orang. Jenis alergen terbanyak yang didapatkan adalah tungau debu rumah dan kacang tanah sebanyak 14 orang (50%). Persentase alergen lain pada hasil uji cukit kulit pada penelitian ini adalah bulu anjing didapatkan pada 13 orang (46,43%),  putih telur 13 orang (46,43%),  udang 12 orang (42,86%), daging sapi 12 orang (42,86%), kuning telur 12 orang (42,86%), kedelai 12 orang (42,86%), coklat 12 orang (42,86%), kopi 12 orang (42,86%), nanas 12 orang (42,86%), kepiting 11 orang (39,29%), cumi 11 orang (39,29%), ikan air tawar 11 orang (39,29%), teh 11 orang (39,29%), kerang 10 orang (35,71%), tongkol 10 orang (35,71%), daging ayam 9 orang (32,14%), serta susu 8 orang (28,57%).Kata kunci: rhinitis alergi, alergen, uji cukit kulit

Background: Allergic rhinitis is a chronic inflammatory condition of the nasal mucosa that occurs as an Imunoglobulin E (IgE) mediated reaction after provocation of allergen. The prevalence of rhinitis in Indonesia reaches 12.4% and still rising. Chronic rhinitis can affect the quality of life, especially daily activities and sleep disturbances. Purpose: This study aimed to determine the correlation between the Score for Allergic Rhinitis (SFAR) and the patient’s quality of life (QOL) using allergic rhinitis mobile phone application. Method: This was an observational analytic research using cross sectional method. The number of samples was 46 with predetermined inclusion and exclusion criteria. The research instrument used was a mobile phone application of SFAR and for quality of life was Visual Analog Scales (VAS) questionnaire. Data analysis was using Shapiro-Wilk for normality test and contingency coefficient test to determine the correlation between variables. Result: The result showed that there was a significant correlation between the Score for Allergic Rhinitis and the quality of life in chronic rhinitis sufferers (p = 0.000). The correlation had uni-direction and moderate strength (r = 0.567). There were 52.17% respondents who stated that rhinitis complaints would be reduced after using nasal drugs/sprays. And for the VAS parameter, the highest number given was 0 in 45.65% respondents, which meant that they did not feel any discomfort. Conclusion: There was a significant correlation between SFAR and quality of life AR sufferers with moderate strength and uni-direction.Keywords: Score for Allergic Rhinitis, quality of life, rhinitis, mobile applicationABSTRAKLatar belakang: Rinitis alergi adalah kondisi inflamasi kronis pada mukosa hidung sebagai reaksi yang dimediasi Imunoglobulin E (IgE) setelah provokasi alergen. Prevalensi rinitis di Indonesia mencapai 12,4 % dan akan terus meningkat. Rinitis kronik dapat memengaruhi kualitas hidup terutama aktivitas sehari-hari dan gangguan tidur. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi Score for Allergic Rhinitis (SFAR) dengan kualitas hidup penderita menggunakan aplikasi rinitis alergi pada telepon genggam. Metode: Penelitian ini berupa analitik observasional dengan desain cross sectional. Sampel yang digunakan sebanyak 46 responden dengan kriteria inklusi dan eksklusi yang sudah ditentukan. Instrumen penelitian menggunakan aplikasi telepon genggam berisi kuisioner SFAR dan kualitas hidup dengan Visual Analog Scales (VAS). Analisis data menggunakan Shapiro-Wilk untuk uji normalitas dan uji koefisien kontingensi untuk mengetahui korelasi antar variabel. Hasil: Didapatkan hasil berupa hubungan korelasi yang bermakna antara skor SFAR dengan kualitas hidup penderita rinitis kronik (p=0,000). Hubungan korelasi tersebut memiliki satu arah dan kekuatan yang sedang (r=0,567). Diperoleh pernyataan dari 52,17% responden bahwa keluhan rinitis akan berkurang setelah minum obat/menggunakan semprot hidung. Untuk parameter VAS didapatkan hasil bahwa angka terbanyak yang diberikan adalah 0 pada 45,65% responden, yang berarti tidak merasakan ketidaknyamanan. Kesimpulan: Terdapat korelasi bermakna antara SFAR dan kualitas hidup penderita AR dengan kekuatan hubungan sedang dan satu arah.Kata kunci: Score for Allergic Rhinitis, kualitas hidup, rinitis, aplikasi telepon genggam