Introduction: Intracerebral hemorrhage (ICH), a form of stroke syndrome results from the rupture of an intracerebral vessel leading to the development of a hematoma in the substance of the brain. Incidence rates are particularly high in Asians and Blacks. Attempts are made to prognosticate ICH patients and manage them accordingly. This is particularly important for the socio-economic profile of the patients availing our services. Methods: All together 90 patients of ICH were taken up in this study done in Gauhati Medical College and Hospital during the period from July 2013 to June 2015. Patients were diagnosed on the basis of a thorough medical history, a full neurological examination, standardized blood tests and CT scan of the brain. Prognostication was done on the basis of clinical and radiological findings. Prognosis was assessed as good or bad outcome on the 15th day based on neurological examination. Statistical analysis was done by using the chi-square test, fisher's t-test and student's t-test wherever applicable. Results: In our study 35.55% patients showed bad outcome. Increasing age, low level of consciousness, low GCS score, bilateral limb weakness, high blood pressure, gaze palsies, pupillary abnormalities and CT brain findings of higher volume (>=30 ml) of hematoma, midline shift, intraventricular extension and a high ICH score were associated with bad outcome.

INTRODUCTION Hepatic encephalopathy is the term used to describe the complex, sometimes irreversible, and variable changes in neuropsychiatric status that can complicate both acute and chronic liver disease. A spectrum of neuropsychiatric abnormalities exists ranging from clinically indiscernible changes in cognition to clinically obvious changes in intellect behaviour, motor function, and consciousness. METHODS We conducted a hospital-based observational descriptive study comprising of 80 patients of chronic liver disease from June 2014-May 2015 who had been diagnosed on the basis of a thorough history, physical examination, including mini-mental status examination, Glasgow Coma Score, biochemical tests including arterial ammonia, radiological findings, EEG and CFF (critical flicker frequency) Tests after excluding other causes of neurological impairment. The patients were admitted in Gauhati Medical College and Hospital, Guwahati, Assam (India) and fulfilled the inclusion and exclusion criteria of the study. Statistical analysis was performed using one way ANOVA method of analysis. RESULTS In our study, 61 patients were male and 19 patients were female. 30% patients were in the third decade of life followed by 26.25% in the fourth decade and 18.75% in the fifth decade. Most of the patients were in Child-Pugh Class C (72.5%) followed by Class A (16.25%) and Class B (11.25%). The patients were assigned grades of hepatic encephalopathy according to the West-Haven classification. Majority of patients were in grade I hepatic encephalopathy (30%) followed by grade III (28.75%) and grade IV (21.25%). The lowest mean arterial ammonia level was found in grade 0 and grade I hepatic encephalopathy-39.2±7.4 mg/dL and 58.7±9.8 mg/dL (mean±standard deviation) respectively and the highest values were found in the highest grades of hepatic encephalopathy-grade III and IV (98.4±10.7 mg/dL and 145.0±17.0 mg/dL respectively). CONCLUSION The arterial ammonia correlates with the grades of hepatic encephalopathy and interventions aimed at reducing the ammonia level improves the outcome and prognosis.